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Quinine |
Quinamm; Quiphile |
Quinine Systematic (IUPAC) name (2-ethenyl-4-azabicyclo[2.2.2]oct-5-yl)- (6-methoxyquinolin-4-yl)-methanol Identifiers CAS number 130-95-0 ATC code M09AA01 P01BC01 PubChem 8549 DrugBank APRD00563 Chemical data Formula C20H24N2O2 Mol. weight 324.417 g/mol Physical data Melt. point 177°C (351°F) Pharmacokinetic data Bioavailability 76 to 88% Protein binding ~70% Metabolism Hepatic (mostly CYP3A4 and CYP2C19-mediated) Half life ~18 hours Excret ...
Wikipedia - [full article]
Quinine Clinical Trials
- Efficacy of Intrarectal Versus Intravenous Quinine for the Treatment of Childhood Cerebral Malaria
ClinicalTrials.gov Identifier: NCT00124267 - Active, not recruiting
Cerebral Malaria
- Influence of Probenecid and Quinine on the Pharmacokinetics of Azidothymidine
ClinicalTrials.gov Identifier: NCT00000706 - Completed
HIV Infections
- Quinine vs. Artemether/Lumefantrine in Uncomplicated Malaria During Pregnancy
ClinicalTrials.gov Identifier: NCT00495508 - Recruiting
Malaria
- Investigation of the Efficacy of Quinine Sulphate Administered Via Taste-Masked Pellets to Children With Falciparum Malaria
ClinicalTrials.gov Identifier: NCT00329134 - Recruiting
Malaria
- Effectiveness of Oral Quinine and Artemether-Lumefantrine in the Treatment of Uncomplicated Malaria in Ugandan Children
ClinicalTrials.gov Identifier: NCT00540202 - Recruiting
Uncomplicated Malaria
- Treatment of Malaria With Quinine Plus Sulfadoxine-Pyrimethamine
ClinicalTrials.gov Identifier: NCT00167739 - Completed
Malaria
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