Tegaserod |
tegaserod maleate; Zelnorm |
Image:Tegaserod.png Tegaserod Systematic (IUPAC) name 1-{[5-(hydroxymethyl)-1H-indol-3-yl]methylideneamino}- 2-pentyl-guanidine Identifiers CAS number 189188-57-6 ATC code A03AE02 PubChem 5487301 DrugBank APRD00096 Chemical data Formula C16H23N5O Mol. weight 301.387 g/mol Pharmacokinetic data Bioavailability 10% Protein binding 98% Metabolism Gastric and hepatic Half life 11 ± 5 hours Excretion Fecal and renal Therapeutic considerations Pre ...
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Tegaserod Clinical Trials
- The Effects of Tegaserod Vs. Placebo on Whole Gut Transit Time in Patients With Chronic Constipation and Dyspepsia
ClinicalTrials.gov Identifier: NCT00277550 - Not yet recruiting
Constipation and Dyspepsia
- Study of Effect of Tegaserod on Small and Large Bowel Transit by Scintigraphic Method
ClinicalTrials.gov Identifier: NCT00563615 - Recruiting
Constipation
- An Evaluation of the Efficacy and Safety of Tegaserod 6 Mg Bid Given Orally to Chinese Patients with Chronic Constipation
ClinicalTrials.gov Identifier: NCT00139568 - Completed
Chronic constipation
- Assessment of Efficacy and Safety of Tegaserod in Male Patients with Chronic Constipation.
ClinicalTrials.gov Identifier: NCT00141089 - Completed
Chronic Constipation
- Efficacy, Safety and Tolerability of Tegaserod in Patients with Chronic Constipation
ClinicalTrials.gov Identifier: NCT00149877 - Completed
Chronic Constipation
- Efficacy of Tegaserod in Relieving the Symptoms of Female Patients with Irritable Bowel Syndrome (IBS), Excluding Those with Predominant Diarrhea IBS
ClinicalTrials.gov Identifier: NCT00142987 - Completed
IBS-C and IBS with mixed bowel habits
- A Study to Assess the Efficacy, Safety and Tolerability of Tegaserod Alone and in Combination with Omeprazole Given Orally in Patients with Symptoms of Symptomatic Gastroespohageal Reflux Disease (sGERD)
ClinicalTrials.gov Identifier: NCT00149851 - Completed
symptomatic gastroespohageal reflux disease
- The Role of Tegaserod Therapy in the Management of Dyspeptic Symptoms in Female Patients on Proton Pump Inhibitors for the Treatment of Heartburn.
ClinicalTrials.gov Identifier: NCT00171470 - Completed
Dyspepsia
- Assessment of Efficacy and Safety of Tegaserod Treatment and Placebo in Women With Dyspepsia
ClinicalTrials.gov Identifier: NCT00232024 - Completed
Dyspepsia
- Assessment of Efficacy and Safety of Tegaserod Treatment and Placebo in Women With Dyspepsia
ClinicalTrials.gov Identifier: NCT00232089 - Completed
Dyspepsia
- Extension Study to Assess the Long-Term Safety of Tegaserod in Women With Symptoms of Dyspepsia
ClinicalTrials.gov Identifier: NCT00232037 - Completed
Dyspepsia
- Extension Study to Assess the Long-Term Safety of Tegaserod in Women With Symptoms of Dyspepsia
ClinicalTrials.gov Identifier: NCT00232102 - Completed
Dyspepsia
- Preference of Tegaserod Vs. PEG 3350 in Patients With Constipation
ClinicalTrials.gov Identifier: NCT00171522 - Completed
Constipation
- Assessment of the Effect of Tegaserod (2 Mg Tid and 6 Mg Tid) on Dyspeptic Symptoms in Diabetic Patients with Symptoms of Diabethic Gastropathy
ClinicalTrials.gov Identifier: NCT00142974 - Terminated
Diabetic Gastropathy
- The Effects of Tegaserod on Mechanical Sensitivity of the Esophagus and Stomach in Patients With Heartburn and Dyspepsia.
ClinicalTrials.gov Identifier: NCT00171457 - Completed
Heartburn; Dyspepsia
- Polyethyleneglycol3350 Vs Tegaserod in Treatment of Patients with Chronic Constipation
ClinicalTrials.gov Identifier: NCT00153140 - Completed
Constipation
- Assessment of the Effects of Tegaserod in the Management of Gastroesophageal Reflux Disease (GERD) in Patients With Incomplete Response to Proton Pump Inhibitors (PPIs).
ClinicalTrials.gov Identifier: NCT00171418 - Completed
Gastroesophageal Reflux Disease (GERD)
- Assessment of the Role of Tegaserod Therapy in the Management of Gastroesophageal Reflux Disease (GERD) Symptoms in Patients With Incomplete Response to Proton Pump Inhibitors (PPIs).
ClinicalTrials.gov Identifier: NCT00171483 - Completed
Gastroesophageal Reflux Disease (GERD)
- Effect of Tegaserod on Gastric Emptying in Patients With Diabetic Gastroparesis
ClinicalTrials.gov Identifier: NCT00390975 - Terminated
Gastroparesis; Diabetes
- Efficacy and Safety of Tegaserod in Opioid-Induced Constipation in Patients With Non-Cancer Pain
ClinicalTrials.gov Identifier: NCT00365820 - Terminated
Constipation
- Effect of Tegaserod on Orocecal Transit in Elderly Chronic Constipation Patients
ClinicalTrials.gov Identifier: NCT00348634 - Terminated
Chronic Constipation
- A Randomized, Double-Blind, Placebo-Controlled Multicenter Study to Assess the Efficacy, Safety and Tolerability of Tegaserod 2 mg Bid vs Placebo in Patients With Chronic Constipation
ClinicalTrials.gov Identifier: NCT00563758 - Terminated
Constipation; Chronic Disease
- Safety and Efficacy of Tegaserod in Opioid-Induced Constipation in Patients With Non-Cancer Pain.
ClinicalTrials.gov Identifier: NCT00399659 - Terminated
Opioid-Induced Constipation
- Safety and Efficacy of Tegaserod in Opioid-Induced Constipation in Patients With Non-Cancer Pain.
ClinicalTrials.gov Identifier: NCT00414024 - Terminated
Opioid-Induced Constipation
- The Effect of Tegaserod on Patterns of Flow in the Small Bowel of Patients With Irritable Bowel Syndrome (IBS)
ClinicalTrials.gov Identifier: NCT00171431 - Terminated
Constipation Predominant - Irritable Bowel Syndrome (IBS-C)

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