Thioguanine |
6-TG; TG |
Tioguanine Systematic (IUPAC) name 2-amino-7H-purine-6-thiol Identifiers CAS number 154-42-7 ATC code L01BB03 PubChem 2723601 DrugBank APRD00290 Chemical data Formula C5H5N5S Mol. weight 167.193 g/mol Pharmacokinetic data Bioavailability 30% (range 14% to 46%) Metabolism Intracellular Half life 80 minutes (range 25-240 minutes) Excretion ? Therapeutic considerations Pregnancy cat. ? Legal status Routes oral Tioguanine (INN), formerly Th ...
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Thioguanine Clinical Trials
- Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Previously Untreated Acute Lymphocytic Leukemia
ClinicalTrials.gov Identifier: NCT00002665 - Active, not recruiting
Thrombocytopenia; Leukemia, Lymphocytic; Neutropenia
- Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia
ClinicalTrials.gov Identifier: NCT00005596 - Active, not recruiting
untreated childhood acute lymphoblastic leukemia
- Combination Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia
ClinicalTrials.gov Identifier: NCT00002816 - Active, not recruiting
Quality of Life; recurrent childhood acute lymphoblastic leukemia
- Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphocytic Leukemia
ClinicalTrials.gov Identifier: NCT00003671 - Active, not recruiting
B-cell childhood acute lymphocytic leukemia; untreated childhood acute lymphocytic leukemia
- Combination Chemotherapy in Treating Children With Lymphoma
ClinicalTrials.gov Identifier: NCT00002590 - Active, not recruiting
stage IV childhood large cell lymphoma; stage IV childhood lymphoblastic lymphoma
- Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
ClinicalTrials.gov Identifier: NCT00016302 - Active, not recruiting
untreated childhood acute lymphoblastic leukemia; T-cell childhood acute lymphoblastic leukemia
- Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia
ClinicalTrials.gov Identifier: NCT00005603 - Active, not recruiting
childhood acute lymphoblastic leukemia in remission; B-cell childhood acute lymphoblastic leukemia
- Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia
ClinicalTrials.gov Identifier: NCT00005585 - Active, not recruiting
childhood acute lymphoblastic leukemia in remission; B-cell childhood acute lymphoblastic leukemia
- Combination Chemotherapy in Treating Adults With Acute Lymphocytic Leukemia
ClinicalTrials.gov Identifier: NCT00002531 - Active, not recruiting
non-T, non-B adult acute lymphoblastic leukemia; untreated adult acute lymphoblastic leukemia; B-cell adult acute lymphoblastic leukemia; ...
- Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00002517 - Active, not recruiting
Myeloid Leukemia; Myelodysplastic Syndromes; Refractory Anemia
- Hormone Therapy Plus Chemotherapy in Treating Children With Acute Lymphocytic Leukemia
ClinicalTrials.gov Identifier: NCT00003437 - Active, not recruiting
recurrent childhood acute lymphoblastic leukemia; untreated childhood acute lymphoblastic leukemia
- Combination Chemotherapy in Treating Children or Adolescents With Newly Diagnosed Lymphoblastic Lymphoma
ClinicalTrials.gov Identifier: NCT00004228 - Active, not recruiting
stage I childhood lymphoblastic lymphoma; stage II childhood lymphoblastic lymphoma; stage III childhood lymphoblastic lymphoma; ...
- Comparison of Different Combination Chemotherapy Regimens in Treating Children With Acute Lymphoblastic Leukemia
ClinicalTrials.gov Identifier: NCT00005945 - Active, not recruiting
untreated childhood acute lymphoblastic leukemia; L1 childhood acute lymphoblastic leukemia; L2 childhood acute lymphoblastic leukemia; ...
- Comparison of Different Combination Chemotherapy Regimens in Treating Infants With Acute Lymphoblastic Leukemia
ClinicalTrials.gov Identifier: NCT00015873 - Active, not recruiting
untreated childhood acute lymphoblastic leukemia
- Combination Chemotherapy in Treating Children With Progressive Brain Tumors
ClinicalTrials.gov Identifier: NCT00002944 - Active, not recruiting
recurrent childhood brain stem glioma; recurrent childhood visual pathway glioma; recurrent childhood cerebellar astrocytoma; ...
- Intensive Compared With Nonintensive Chemotherapy in Treating Older Patients with Acute Myeloid Leukemia or Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00005823 - Active, not recruiting
Acute Myeloid Leukemia; adult acute monoblastic and acute monocytic leukemia; atypical chronic myeloid leukemia; Chronic Myelomonocytic Leukemia; ...
- Combination Chemotherapy, Biological Therapy, and Bone Marrow Transplantation in Treating Patients With Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00002658 - Active, not recruiting
Myeloid Leukemia; Neutropenia
- Combination Chemotherapy Followed by Melphalan and Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00004056 - Active, not recruiting
childhood acute megakaryocytic leukemia (M7); untreated childhood acute myeloid leukemia; ...
- Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Acute Promyelocytic Leukemia
ClinicalTrials.gov Identifier: NCT00002701 - Active, not recruiting
untreated adult acute myeloid leukemia; adult acute promyelocytic leukemia (M3)
- Combination Chemotherapy in Treating Children With Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00003423 - Active, not recruiting
stage I childhood large cell lymphoma; stage III childhood lymphoblastic lymphoma; stage III childhood large cell lymphoma; ...
- Combination Chemotherapy With or Without Donor Bone Marrow Transplantation in Treating Infants With Previously Untreated Acute Lymphoblastic Leukemia
ClinicalTrials.gov Identifier: NCT00022126 - Active, not recruiting
untreated childhood acute lymphoblastic leukemia; L1 childhood acute lymphoblastic leukemia; L2 childhood acute lymphoblastic leukemia; ...
- Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
ClinicalTrials.gov Identifier: NCT00103285 - Recruiting
untreated childhood acute lymphoblastic leukemia; B-cell childhood acute lymphoblastic leukemia
- Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
ClinicalTrials.gov Identifier: NCT00109837 - Recruiting
L1 adult acute lymphoblastic leukemia; L2 adult acute lymphoblastic leukemia; untreated adult acute lymphoblastic leukemia
- Combination Chemotherapy Plus Steroid Therapy in Treating Children With Acute Lymphoblastic Leukemia or Lymphoblastic Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00003728 - Recruiting
acute undifferentiated leukemia; childhood acute lymphoblastic leukemia; childhood lymphoblastic lymphoma
- Dexamethasone Compared With Prednisone During Induction Therapy and Methotrexate With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia
ClinicalTrials.gov Identifier: NCT00075725 - Recruiting
untreated childhood acute lymphoblastic leukemia; B-cell childhood acute lymphoblastic leukemia; untreated adult acute lymphoblastic leukemia; ...
- Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia
ClinicalTrials.gov Identifier: NCT00002744 - Completed
L1 childhood acute lymphocytic leukemia; L2 childhood acute lymphocytic leukemia; untreated childhood acute lymphocytic leukemia
- Combination Chemotherapy in Treating Children With Acute Lymphocytic Leukemia
ClinicalTrials.gov Identifier: NCT00002812 - Completed
L2 childhood acute lymphoblastic leukemia; untreated childhood acute lymphoblastic leukemia; L1 childhood acute lymphoblastic leukemia
- Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myelogenous Leukemia or Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00002798 - Completed
Myeloid Leukemia; Refractory Anemia
- Chemotherapy in Treating Children With Down Syndrome and Myeloproliferative Disorder, Acute Myelogenous Leukemia, or Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00003593 - Completed
childhood acute monocytic leukemia; childhood acute myeloid leukemia and other myeloid malignancies; Chronic Myelomonocytic Leukemia; ...
- Stem Cell Transplantation Compared With Standard Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia in First Remission
ClinicalTrials.gov Identifier: NCT00002514 - Completed
adult acute lymphoblastic leukemia in remission

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