Tizanidine |
Zanaflex |
Tizanidine Systematic (IUPAC) name 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)- 8-thia-7,9-diazabicyclo[4.3.0] nona-2,4,6, 9-tetraen-5-amine Identifiers CAS number 51322-75-9 ATC code M03BX02 PubChem 5487 DrugBank APRD00128 Chemical data Formula C9H8ClN5S Mol. weight 253.712 g/mol Pharmacokinetic data Bioavailability ? Protein binding 30% Metabolism ? Half life 2.5 hours Excretion ? Therapeutic considerations Pregnancy cat. ? Leg ...
Wikipedia - [full article]
Tizanidine Clinical Trials
- Comparison of safety and efficacy of tizanidine hydrochloride capsules versus Zanaflex® (tizanidine hydrochloride tablets) taken while in the fed state (just after a meal) and in the fasted state (before a meal) in patients with moderate to severe sp
ClinicalTrials.gov Identifier: NCT00047580 - Completed
Multiple Sclerosis; Muscle Spasticity; Spinal Cord Injury; Stroke
- Study of Nighttime Dosing of Sublingual Tizanidine (12 mg) in Multiple Sclerosis (MS) Patients With Significant Spasticity
ClinicalTrials.gov Identifier: NCT00358293 - Completed
Muscle Spasticity
- Pilot, Proof-of-Concept Study of Sublingual Tizanidine in Children With Chronic Traumatic Brain Injury (TBI)
ClinicalTrials.gov Identifier: NCT00287157 - Completed
Traumatic Brain Injury

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