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Zonisamide |
Zonegran |
Zonisamide Systematic (IUPAC) name 1,2-benzisoxazole-3-methanesulfonamide Identifiers CAS number 68291-97-4 ATC code N03AX15 PubChem 5734 DrugBank APRD00004 Chemical data Formula C8H8N2O3S Mol. weight 212.227 g/mol Physical data Melt. point 162°C (324°F) Pharmacokinetic data Bioavailability ? Protein binding 40% Metabolism Hepatic Half life 105 hours in red blood cells, 63 hours in plasma Excretion Renal Therapeutic considerations Pregna ...
Wikipedia - [full article]
Zonisamide Clinical Trials
- The Effects of Zonisamide on Alcohol Dependence
ClinicalTrials.gov Identifier: NCT00406692 - Recruiting
Alcoholism
- Zonisamide for Weight Reduction in Obese Adults
ClinicalTrials.gov Identifier: NCT00275834 - Recruiting
Obesity
- OPEN LABEL, ZONEGRAN (ZONISAMIDE) IN PARTIAL ONSET SEIZURES
ClinicalTrials.gov Identifier: NCT00215592 - Active, not recruiting
Epilepsy
- Efficacy and Safety of an Add-on Treatment With Zonisamide in Adults With Focal Epileptic Seizures With or Without Secondary Generalization
ClinicalTrials.gov Identifier: NCT00165828 - Recruiting
Epilepsy
- Patient, Provider, and Healthcare System Factors Associated with in Suboptimal Prescribing for Older Patients with Epilepsy
ClinicalTrials.gov Identifier: NCT00144001 - Active, not recruiting
Epilepsy
- A Safety/Efficacy Trial of Zonisamide for Essential Tremor
ClinicalTrials.gov Identifier: NCT00223743 - Active, not recruiting
Essential Tremor
- Open Label Study of Zonisamide in the Treatment of Epilepsy in Patients With Mental Retardation
ClinicalTrials.gov Identifier: NCT00298818 - Active, not recruiting
Epilepsy; Mental Retardation; Developmental Disabilities
- Dose Response Study of Zonegran in Patients With Newly Diagnosed Epilepsy
ClinicalTrials.gov Identifier: NCT00056576 - Active, not recruiting
Epilepsy, Complex Partial
- A Study to Measure the Safety and Effectiveness of Zonisamide in Subjects with Migraine Headache
ClinicalTrials.gov Identifier: NCT00055484 - Completed
Migraine Headache
- A Study in Evaluating the Efficacy and Safety of Zonisamide and Lamotrigine (Lamictal) for Subjects With Refractory Simple Partial, Complex Partial or Partial With Secondary Generalized Seizures
ClinicalTrials.gov Identifier: NCT00292461 - Recruiting
Epilepsy
- A Double-Blind Study to Compare the Efficacy and Safety of Zonisamide and Carbamazepine as Monotherapy, in Newly Diagnosed Partial Epilepsy
ClinicalTrials.gov Identifier: NCT00477295 - Not yet recruiting
Epilepsy
- A Multicenter, Placebo-Controlled, Double-Blind Study to Evaluate the Efficacy and Safety of Zonisamide in the Treatment of Partial Seizure
ClinicalTrials.gov Identifier: NCT00327717 - Not yet recruiting
Partial Seizures
- A Multicenter Comparative Trial of Zonisamide and Topiramate as Initial Monotherapy in Untreated Epilepsies
ClinicalTrials.gov Identifier: NCT00154076 - Recruiting
Pending - We have submitted to each center''s IRB and waiting for results to Epilepsy.
- Zonisamide for Fibromyalgia & Migraine
ClinicalTrials.gov Identifier: NCT00259636 - Recruiting
Fibromyalgia; Migraine
- A Study of Zonisamide to Prevent Olanzapine-Associated Weight Gain
ClinicalTrials.gov Identifier: NCT00363376 - Not yet recruiting
Weight Gain
- Open-label Adjunctive Zonisamide for Bipolar Disorder
ClinicalTrials.gov Identifier: NCT00047567 - Terminated
Bipolar Disorders
- Efficacy and Safety of Adjunctive Zonisamide in Paediatric Partial Onset Seizures (CATZ Study)
ClinicalTrials.gov Identifier: NCT00566254 - Not yet recruiting
Epilepsy; Paediatric Partial Onset Seizures
- Safety and Efficacy of Different Combinations of Zonisamide-CR Plus Bupropion-SR to Treat Uncomplicated Obesity
ClinicalTrials.gov Identifier: NCT00339014 - Completed
Obesity
Resources
- Zonegran (Drug Digest)
- Zonegran Consumer Information (U.S. Food and Drug Administration)
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