Medium-chain acyl-coenzyme A dehydrogenase deficiency |
ACADM deficiency; MCAD deficiency; MCADD; MCADH deficiency |
Medium-chain acyl-coenzyme A dehydrogenase deficiency is one of a group of conditions that is associated with inborn errors of metabolism in fatty acid oxidation. It is due to defects in the enzyme complex known as medium chain acyl dehydrogenase (MCAD) and reduced activity of this complex. It is recognised as one of the causes of sudden infant death syndrome (SIDS, "cot death" or "crib death"). MCAD deficiency is considered sufficient explanation for sudden death. This condition is better ...
Wikipedia - [full article]
Medium-chain acyl-coenzyme A dehydrogena... Clinical Trials
- PET Imaging of GABA Receptors in Succinic Semialdehyde Dehydrogenase Deficiency
ClinicalTrials.gov Identifier: NCT00246870 - Recruiting
Succinic Semialdehyde Dehydrogenase Deficiency; SSADH Deficiency
- A Test to Predict the Hemolytic Potential of Drugs in G6PD Deficiency
ClinicalTrials.gov Identifier: NCT00076323 - Suspended
Glucosephosphate Dehydrogenase Deficiency; Favism
- Mutation Analysis of 17βhydroxysteroid Dehydrogenase 3 Deficiency
ClinicalTrials.gov Identifier: NCT00173654 - Recruiting
Pseudohermaphroditism
- Phase II Randomized Study of Tin Mesoporphyrin for Neonatal Hyperbilirubinemia
ClinicalTrials.gov Identifier: NCT00004381 - Completed
Glucosephosphate Dehydrogenase Deficiency; Hyperbilirubinemia; Hemolytic Disease of Newborn
- Prepubertal Children with Growth Failure Associated with Primary IGF-1 Deficiency
ClinicalTrials.gov Identifier: NCT00125164 - Active, not recruiting
Insulin-Like Growth Factor-1 Deficiency; Primary IGF-1 Deficiency
- Effects of Medium Chain Triglyceride Oil, Versus Olive Oil, for Weight Loss
ClinicalTrials.gov Identifier: NCT00529919 - Completed
Overweight
- Recombinant Human Insulin-Like Growth Factor (rhIGF-1)Treatment of Short Stature Associated with IGF-1 Deficiency
ClinicalTrials.gov Identifier: NCT00125190 - Active, not recruiting
Insulin-Like Growth Factor-1 Deficiency; Primary IGF-1 Deficiency; IGF-1
- Coenzyme Q10 in Relieving Treatment-Related Fatigue in Women With Breast Cancer
ClinicalTrials.gov Identifier: NCT00096356 - Recruiting
Breast Cancer; Fatigue
- Gene Therapy for Patients with Leukocyte Adherence Deficiency (Follow-Up of Phase 1 Trial)
ClinicalTrials.gov Identifier: NCT00023010 - Active, not recruiting
Leukocyte Adhesion Deficiency Syndrome
- 4-PBA: Will it increase the level of Alpha 1-Antitrypsin(AAT) in persons with AAT deficiency?
ClinicalTrials.gov Identifier: NCT00067756 - Active, not recruiting
alpha 1-Antitrypsin Deficiency
- Vaccine Therapy in Treating Patients With Melanoma of the Eye
ClinicalTrials.gov Identifier: NCT00036816 - Active, not recruiting
ciliary body and choroid melanoma, medium/large size
- Phase I Study of Retrovirus-Mediated Transfer of cDNA for Human CD18 into Peripheral Blood Repopulating Cells of Patients With Leukocyte Adherence Deficiency
ClinicalTrials.gov Identifier: NCT00004470 - Active, not recruiting
Leukocyte Adhesion Deficiency Syndrome
- Open Label Phase 3 Study of NABI-IGIV 10% [(HUMAN)] In Subjects With Primary Immune Deficiency Disorders (PIDD)
ClinicalTrials.gov Identifier: NCT00538915 - Recruiting
Primary Immune Deficiency Disorders; Antibody Deficiency Syndromes
- Bezafibrate Trial in CPT2 Deficiency
ClinicalTrials.gov Identifier: NCT00336167 - Recruiting
Carnitine Palmitoyl Transferase 2 Deficiency
- Experimental Gene Transfer Procedure to Treat Alpha 1-Antitrypsin Deficiency
ClinicalTrials.gov Identifier: NCT00377416 - Active, not recruiting
Alpha 1-Antitrypsin Deficiency
- Association of Dihydropyrimidine Dehydrogenase (DPYD) Variants With Toxicity Related to Capecitabine
ClinicalTrials.gov Identifier: NCT00478686 - Recruiting
Breast Cancer
- Efficacy and Safety of a High Dosage Compared to the Label Dosage of Somatropin in Early Pubertal Stage Children With Growth Hormone Deficiency
ClinicalTrials.gov Identifier: NCT00191165 - Active, not recruiting
Growth Hormone Deficiency
- The Efficacy of Coenzyme Q10 And Curcumin in Patients With Myelodysplastic Syndromes
ClinicalTrials.gov Identifier: NCT00247026 - Not yet recruiting
Myelodysplastic Syndrome
- A Multi-Dose Study to Assess Tolerability, Safety and Pharmacology of hGH-ViaDerm™ System in Adults With GH-Deficiency
ClinicalTrials.gov Identifier: NCT00455260 - Recruiting
Growth Hormone Deficiency
- A Clinical Study of the PK, Efficacy and Safety of Omr-IgG-am IGIV in Subjects With Primary Immune Deficiency Diseases
ClinicalTrials.gov Identifier: NCT00468273 - Recruiting
Immunologic Deficiency Syndromes
- Ferinject® Assessment in Patients With IRon Deficiency and Chronic Heart Failure (FAIR-HF)
ClinicalTrials.gov Identifier: NCT00520780 - Recruiting
Chronic Heart Failure; Iron Deficiency; Iron Deficiency Anemia; Anaemia
- Intramyocardial Injection of Autologous Aldehyde Dehydrogenase-Bright Stem Cells for Therapeutic Angiogenesis
ClinicalTrials.gov Identifier: NCT00314366 - Recruiting
Coronary Artery Disease
- Helicobacter Pylori and Iron Deficiency: Prevalence of Association and Effect of Therapy
ClinicalTrials.gov Identifier: NCT00475527 - Active, not recruiting
Anemia, Iron-Deficiency; Helicobacter Pylori
- Zemaira in Subjects With Emphysema Due to API Deficiency
ClinicalTrials.gov Identifier: NCT00261833 - Recruiting
Alpha1-Proteinase Inhibitor Deficiency
- Comparative Results of Maxillary Deficiency Treatment by Tongue Plate and Facemask in Growing Patients
ClinicalTrials.gov Identifier: NCT00519415 - Recruiting
Orthodontic Angle Class Three; Maxillary Deficiency
- Vaccine Therapy With or Without Sargramostim in Treating Patients Who Have Undergone Surgery for Melanoma
ClinicalTrials.gov Identifier: NCT00089063 - Active, not recruiting
stage II melanoma; stage III melanoma; Stage IV Melanoma; iris melanoma; ciliary body and choroid melanoma, medium/large size; ...
- A Study of the Efficacy and Safety of Genz-112638 in Type 1 Gaucher Patients
ClinicalTrials.gov Identifier: NCT00358150 - Active, not recruiting
Gaucher Disease, Type 1; Cerebroside Lipidosis Syndrome; Glucocerebrosidase Deficiency Disease; Glucosylceramide Beta-Glucosidase Deficiency Disease; Gaucher Disease, Non-Neuronopathic Form
- H. Pylori Eradication Trial to Reduce Iron Deficiency in Children
ClinicalTrials.gov Identifier: NCT00364104 - Recruiting
Iron Deficiency
- Consequence of Lifetime Isolated Growth Hormone Deficiency
ClinicalTrials.gov Identifier: NCT00149708 - Recruiting
Growth Hormone Deficiency
- Recombinant Human Antithrombin (rhAT) in Patients with Hereditary Antithrombin Deficiency Undergoing Surgery or Delivery
ClinicalTrials.gov Identifier: NCT00110513 - Recruiting
Antithrombin III Deficiency
- Vitamin D Deficiency, Insulin Resistance and FGF-23
ClinicalTrials.gov Identifier: NCT00491322 - Recruiting
Vitamin D Deficiency
- Estrogen Deficiency and Cardiovascular Disease in Premenopausal Women
ClinicalTrials.gov Identifier: NCT00572858 - Recruiting
Estrogen Deficiency
- Safety and Efficacy of Cerezyme® Infusions Every 4 Weeks Versus Every 2 Weeks in Type 1 Gaucher Disease
ClinicalTrials.gov Identifier: NCT00364858 - Active, not recruiting
Gaucher Disease, Type 1; Cerebroside Lipidosis Syndrome; Glucocerebrosidase Deficiency Disease; Glucosylceramide Beta-Glucosidase Deficiency Disease; Gaucher Disease, Non-Neuronopathic Form
- A Single Dose Study to Evaluate the PK-PD Response and Safety of PHA-794428 in Children With Growth Hormone Deficiency
ClinicalTrials.gov Identifier: NCT00314938 - Recruiting
Growth Hormone Deficiency
- Peptide Vaccine, Montanide ISA 51, and CpG 7909 in Treating Patients With Resected Stage IIC, Stage III, or Stage IV Melanoma
ClinicalTrials.gov Identifier: NCT00085189 - Active, not recruiting
stage II melanoma; stage III melanoma; Stage IV Melanoma; iris melanoma; ciliary body and choroid melanoma, medium/large size; ...
- A Study To Evaluate The Dose Response And Safety Of PHA-794428 In Adults With Growth Hormone Deficiency
ClinicalTrials.gov Identifier: NCT00308464 - Recruiting
Growth Hormone Deficiency
- Lenalidomide in Treating Patients With Stage IV Eye Melanoma
ClinicalTrials.gov Identifier: NCT00112606 - Recruiting
ciliary body and choroid melanoma, medium/large size; extraocular extension melanoma; iris melanoma; recurrent intraocular melanoma
- Volume Deficit Prior to Minor and Medium Sized Surgery and During Epidural Anaesthesia
ClinicalTrials.gov Identifier: NCT00380107 - Recruiting
Hypovolemia
- Phase III Trial of Coenzyme Q10 in Mitochondrial Disease
ClinicalTrials.gov Identifier: NCT00432744 - Recruiting
Mitochondrial Diseases
- Characterization of Hyperparathyroidism and Vitamin D Deficiency in Obesity
ClinicalTrials.gov Identifier: NCT00288873 - Active, not recruiting
Vitamin D Deficiency; Secondary Hyperparathyroidism; Obesity
- Molecular and Clinical Studies of Primary Immunodeficiency diseases
ClinicalTrials.gov Identifier: NCT00006319 - Recruiting
Immunologic Deficiency Syndrome
- rhGH and rhIGF-1 Combination Therapy in Children With Short Stature Associated With IGF-1 Deficiency
ClinicalTrials.gov Identifier: NCT00572156 - Not yet recruiting
Insulin-Like Growth Factor-1 Deficiency
- Sibling Oocyte Study of Medium for IVF/ICSI With no Human Serum Albumine
ClinicalTrials.gov Identifier: NCT00541892 - Recruiting
In Vitro Fertilization; Infertility
- Treatment of Adults With Growth Hormone Deficiency
ClinicalTrials.gov Identifier: NCT00294619 - Recruiting
Pituitary Disorders; Adult Growth Hormone Deficiency
- Experimental Gene Transfer Procedure to Treat Alpha 1-Antitrypsin Deficiency
ClinicalTrials.gov Identifier: NCT00430768 - Recruiting
Alpha 1-Antitrypsin Deficiency
- The Use of High Resolution Chest Computed Tomography in Alpha-1 Antitrypsin Deficiency
ClinicalTrials.gov Identifier: NCT00532805 - Recruiting
Alpha-1 Antitrypsin Deficiency
- Pharmacokinetics of Leptin Administration During Fasting
ClinicalTrials.gov Identifier: NCT00140205 - Active, not recruiting
energy deficiency due to short-term fasting
- Phase I Study of Adenoviral Vector Mediated Gene Transfer for Ornithine Transcarbamylase in Adults with Partial Ornithine Transcarbamylase Deficiency
ClinicalTrials.gov Identifier: NCT00004498 - Active, not recruiting
Ornithine Transcarbamylase Deficiency Disease
- Safety and Efficacy of PRO 542 in the Treatment of HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00055185 - Active, not recruiting
HIV Infections; Acquired Immune Deficiency Syndrome
- Interferon alfa-2b in Treating Patients With Melanoma and Early Lymph Node Metastasis
ClinicalTrials.gov Identifier: NCT00004196 - Active, not recruiting
stage I melanoma; stage II melanoma; stage III melanoma
- Anti-Oxidant Treatment of Alzheimer''s Disease
ClinicalTrials.gov Identifier: NCT00117403 - Active, not recruiting
Alzheimer''s Disease
- Growth Hormone and Chromosome 18q- Abnormal Growth
ClinicalTrials.gov Identifier: NCT00134420 - Active, not recruiting
Chromosome 18; Growth Hormone Deficiency
- International Collaborative Gaucher Group (ICGG) Gaucher Registry
ClinicalTrials.gov Identifier: NCT00358943 - Recruiting
Gaucher Disease; Cerebroside Lipidosis Syndrome; Glucocerebrosidase Deficiency Disease; Glucosylceramide Beta-Glucosidase Deficiency Disease
- Dietary Cholesterol and Defects in Cholesterol Synthesis in Mevalonate Kinase Deficiency
ClinicalTrials.gov Identifier: NCT00260299 - Recruiting
Mevalonic Aciduria; Mevalonate Kinase Deficiency; Immune System Diseases; Periodic Fever Syndromes, Hereditary; Lipid Metabolism, Inborn Errors
- Genetic Basis of Primary Immunodeficiencies
ClinicalTrials.gov Identifier: NCT00001788 - Recruiting
Immunologic Deficiency Syndrome
- Examining Genetic Differences Among People With 21-Hydroxylase Deficiency
ClinicalTrials.gov Identifier: NCT00542841 - Recruiting
21-Hydroxylase Deficiency
- The Prevalence of Vitamin D Deficiency and Effects of Vitamin D Supplementation in HIV-1 Infected Patients
ClinicalTrials.gov Identifier: NCT00306410 - Recruiting
Vitamin D Deficiency; HIV Infections
- Effects of Growth Hormone Administration on Cardiovascular Risk in Cured Acromegalics With Growth Hormone Deficiency
ClinicalTrials.gov Identifier: NCT00182091 - Recruiting
Acromegaly; Growth Hormone Deficiency; Pituitary Disease
- Study of Early Versus Delayed Carotid Endarterectomy (CEA) for Small to Medium-Sized Ischemic Stroke Caused by High-Grade Carotid Stenosis
ClinicalTrials.gov Identifier: NCT00315562 - Active, not recruiting
Stroke; Carotid Stenosis
- Iron Supplementation Among Adolescent Girls in India
ClinicalTrials.gov Identifier: NCT00198848 - Recruiting
Iron deficiency anemia
- Treatment of Anemia in the 2nd Year of Life. Comparison of the Efficacy of Two Different Iron Preparations.
ClinicalTrials.gov Identifier: NCT00248716 - Recruiting
Iron Deficiency; Anemia
- Intravenous or Hepatic Arterial Infusion of Fotemustine in Treating Patients With Unresectable Liver Metastases From Eye Melanoma
ClinicalTrials.gov Identifier: NCT00110123 - Recruiting
liver metastases; ciliary body and choroid melanoma, medium/large size; iris melanoma; extraocular extension melanoma; recurrent intraocular melanoma
- Growth Hormone Administration and Its Effects on Cardiovascular Risk Factors in Growth Hormone Deficient Women
ClinicalTrials.gov Identifier: NCT00136032 - Active, not recruiting
Growth Hormone Deficiency; Pituitary Tumor; Pituitary Disease
- Detection and Characterization of Host Defense Defects
ClinicalTrials.gov Identifier: NCT00001355 - Recruiting
Immunologic Deficiency Syndrome; Infection
- Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies
ClinicalTrials.gov Identifier: NCT00006054 - Active, not recruiting
Immunologic Deficiency Syndromes; Chediak-Higashi Syndrome; Common Variable Immunodeficiency; Graft Versus Host Disease; ...
- Treatment of Children and Adolescents With Growth Failure Associated With Primary Insulin-Like Growth Factor-1 (IGF-1) Deficiency
ClinicalTrials.gov Identifier: NCT00330668 - Recruiting
Primary IGF-1 Deficiency; Growth Disorders
- The Effect of Early Iron Deficiency on Developmental Brain and Behavior in Infants
ClinicalTrials.gov Identifier: NCT00515918 - Not yet recruiting
Iron Deficiency
- Ig NextGen 10% in Patients With Primary Immune Deficiency (PID)
ClinicalTrials.gov Identifier: NCT00405184 - Recruiting
Primary Immune Deficiency (PID)
- Zinc Deficiency in HIV - 1
ClinicalTrials.gov Identifier: NCT00149552 - Active, not recruiting
HIV; alcohol & drug use; zinc; zinc deficiency
- Prevention of Iron Deficiency in 2nd Year of Life
ClinicalTrials.gov Identifier: NCT00479102 - Not yet recruiting
Iron Deficiency; Anemia
- Effects of Growth Hormone on Glucose and Protein Metabolism in Children With Growth Hormone Deficiency
ClinicalTrials.gov Identifier: NCT00362063 - Recruiting
Growth Hormone Deficiency
- Use of Labeled Glucose to Study Lymphocyte Replication and Survival in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00001651 - Recruiting
HIV Infection; Immunologic Deficiency Syndrome
- Endocrine Dysfunction and Growth Hormone Deficiency in Children with Optic Nerve Hypoplasia.
ClinicalTrials.gov Identifier: NCT00140413 - Recruiting
Optic Nerve Hypoplasia; Growth Hormone Deficiency; Septo-Optic dysplasia; Hypopituitarism
- Growth Hormone Deficiency in Chronic Heart Failure: an Observational Study
ClinicalTrials.gov Identifier: NCT00511927 - Recruiting
Ischemic Heart Disease; Dilative Cardiomyopathy; Heart Failure; Growth Hormone Deficiency
- Prevention of Vitamin D Deficiency
ClinicalTrials.gov Identifier: NCT00494104 - Recruiting
Vitamin D Deficiency
- Safety Study of rhASM Enzyme Replacement Therapy in Adults With Acid Sphingomyelinase Deficiency (Niemann-Pick Disease)
ClinicalTrials.gov Identifier: NCT00410566 - Recruiting
Acid Sphingomyelinase Deficiency; Niemann-Pick Disease
- An Open-label Pilot Study of Coenzyme Q10 in Steroid-Treated Duchenne Muscular Dystrophy
ClinicalTrials.gov Identifier: NCT00033189 - Completed
Muscular Dystrophy, Duchenne
- Cystatin C as an Early Marker of Contrast-Medium Nephropathy in Cardiac Catheterization Patients
ClinicalTrials.gov Identifier: NCT00467311 - Recruiting
Contrast Induced Nephropathy; Acute Renal Failure
- Medium-Dose UVA1 Versus Narrow-Band UVB in Atopic Dermatitis
ClinicalTrials.gov Identifier: NCT00419406 - Recruiting
Atopic Dermatitis
- Study of Genetic and Molecular Defects in Primary Immunodeficiency Disorders
ClinicalTrials.gov Identifier: NCT00004341 - Active, not recruiting
X-linked agammaglobulinemia; X-linked hyper IgM syndrome; Wiskott-Aldrich Syndrome; Leukocyte Adhesion Deficiency Syndrome
- I-125 Versus Pd-103 for Medium Risk Prostate Cancer
ClinicalTrials.gov Identifier: NCT00486499 - Recruiting
Prostate Cancer
- Investigation of the Human Immune Response in Normal Subjects and Patients with Disorders of the Immune System and Cancer
ClinicalTrials.gov Identifier: NCT00001582 - Recruiting
Communicable Disease; Immunologic Deficiency Syndrome; Neoplasm
- Interest of Biofer ® Compound Used in Blédilait Follow on Milk in Infant With Latent Iron Deficiency
ClinicalTrials.gov Identifier: NCT00554814 - Not yet recruiting
Latent Iron Deficiency
- Iodine Status in Pregnant Women and Their Newborns: is Congenital Hypothyroidism Related to Iodine Deficiency in Pregnancy?
ClinicalTrials.gov Identifier: NCT00505479 - Recruiting
Congenital Hypothyroidism; Pregnancy; Iodine Deficiency
- Effects of Coenzyme Q10 in Progressive Supranuclear Palsy (PSP)
ClinicalTrials.gov Identifier: NCT00382824 - Recruiting
Progressive Supranuclear Palsy; Atypical Parkinsonism
- Rold of Leptin in the Neuroendocrine and Immune Response to Fasting
ClinicalTrials.gov Identifier: NCT00140231 - Recruiting
energy deficiency associated with short-term fasting
- Effect of Branched Chain Amino Acids on Muscle
ClinicalTrials.gov Identifier: NCT00170144 - Recruiting
Healthy
- Aralast alpha1-Proteinase Inhibitor Surveillance Study
ClinicalTrials.gov Identifier: NCT00313144 - Active, not recruiting
Alpha 1-Antitrypsin Deficiency
- Somatropin Treatment in Patients With SHOX Deficiency and Turner Syndrome
ClinicalTrials.gov Identifier: NCT00190658 - Active, not recruiting
Failure to Thrive
- Predictive Markers in GHD and TS Children Treated With SAIZEN®
ClinicalTrials.gov Identifier: NCT00256126 - Active, not recruiting
Growth Hormone Deficiency
- Efficacy and Safety of Testogel® in Men With Partial Androgen Deficiency of Aging Males (PADAM)
ClinicalTrials.gov Identifier: NCT00185198 - Active, not recruiting
Hypogonadism
- A Trial of the Pharmacokinetics, Safety, and Tolerability of Subcutaneous Gamunex® in Primary Immunodeficiency
ClinicalTrials.gov Identifier: NCT00389324 - Active, not recruiting
Immunologic Deficiency Syndrome
- Iron Therapy in Colo-Rectal Neoplasm and Iron Deficiency Anemia: Intravenous Iron Sucrose Versus Oral Ferrous Sulphate.
ClinicalTrials.gov Identifier: NCT00199277 - Not yet recruiting
Colorectal Neoplasm; Iron deficiency anemia
- Relationship Between Folic Acid and Warfarin Metabolism and Effect
ClinicalTrials.gov Identifier: NCT00162409 - Recruiting
Folic Acid Deficiency
- Does Treatment of Hypovitaminosis D Increase Calcium Absorption?
ClinicalTrials.gov Identifier: NCT00581828 - Active, not recruiting
Osteoporosis; Osteopenia; Vitamin D Deficiency; Hypoparathyroidism; Hypercalciuria; Hypercalcemia
- Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Efficacy and Pharmacokinetics of Myozyme in Patients with Late-Onset Pompe Disease.
ClinicalTrials.gov Identifier: NCT00158600 - Active, not recruiting
Pompe Disease (Late-onset); Glycogen storage disease type II (GSD-II); Acid Maltase Deficiency Disease; Glycogenosis 2
- Gastrointestinal Evaluation in Young Men With Iron Deficiency Anemia
ClinicalTrials.gov Identifier: NCT00498511 - Not yet recruiting
Anemia, Iron-Deficiency
- Parkinson's disease treatment with coenzyme Q10
ClinicalTrials.gov Identifier: NCT00004731 - Completed
Parkinson's Disease
- Safety and Efficacy of Intravenous Immunoglobulin IgPro10 in Patients With Primary Immunodeficiencies (PID)
ClinicalTrials.gov Identifier: NCT00322556 - Active, not recruiting
Agammaglobulinemia; IgG Deficiency; Common Variable Immunodeficiency
- Umbilical Cord Clamping and Infant Iron Status
ClinicalTrials.gov Identifier: NCT00298051 - Active, not recruiting
Iron-Deficiency Anemia

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