Very long-chain acyl-coenzyme A dehydrogenase deficiency

ACADVL; acyl-CoA dehydrogenase very long chain deficiency; VLCAD deficiency; VLCAD-C; VLCAD-H

Very long-chain acyl-coenzyme A dehydrogenase deficiency is a condition that prevents the body from converting certain fats to energy, particularly during periods without food. People with this disorder have inadequate levels of an enzyme that breaks down a group of fats called very long-chain fatty acids. Typically, initial signs and symptoms of this disorder occur during infancy and include low blood sugar (hypoglycemia), lack of energy (lethargy), and muscle weakness. There is also a hig ...