Gaucher disease, type 1 Clinical Trials

• A Study of the Efficacy and Safety of Genz-112638 in Type 1 Gaucher Patients
  ClinicalTrials.gov Identifier: NCT00358150 - Active, not recruiting
  Gaucher Disease, Type 1; Cerebroside Lipidosis Syndrome; Glucocerebrosidase Deficiency Disease; Glucosylceramide Beta-Glucosidase Deficiency Disease; Gaucher Disease, Non-Neuronopathic Form
  
• Safety and Efficacy of Cerezyme® Infusions Every 4 Weeks Versus Every 2 Weeks in Type 1 Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00364858 - Active, not recruiting
  Gaucher Disease, Type 1; Cerebroside Lipidosis Syndrome; Glucocerebrosidase Deficiency Disease; Glucosylceramide Beta-Glucosidase Deficiency Disease; Gaucher Disease, Non-Neuronopathic Form
  
• Open-Label Extension Study Evaluating Long Term Safety in Patients With Type 1 Gaucher Disease Receiving DRX008A (ERT)
  ClinicalTrials.gov Identifier: NCT00391625 - Active, not recruiting
  Gaucher Disease, Type 1
  
• Safety Study of AT2101 in Adult Patients With Type 1 Gaucher Disease Currently Receiving Enzyme Replacement Therapy
  ClinicalTrials.gov Identifier: NCT00433147 - Recruiting
  Gaucher Disease, Type 1
  
• Multicenter Open-Label Study of GA-GCB Enzyme Replacement Therapy in Type 1 Gaucher Disease Patients Previously Treated With Imiglucerase
  ClinicalTrials.gov Identifier: NCT00478647 - Recruiting
  Gaucher Disease, Type 1
  
• Oral Miglustat in Adult Patients With Stable Type 1 Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00319046 - Recruiting
  Type 1 Gaucher Disease
  
• A Multicenter Study of the Efficacy of Cerezyme in Testing Skeletal Disease in Patients With Type I Gaucher Disease.
  ClinicalTrials.gov Identifier: NCT00365131 - Completed
  Gaucher Disease Type I; Cerebroside Lipidosis Syndrome; Clucocerebrosidase Deficiency Disease; Glucosylceramide Beta-Glucosidase Deficiency Disease; Gaucher Disease, Non-Neuronopathic Form
  
• A Multicenter, Randomized, Double-Blind, Parallel-Group Study of Gene-Activated® Human Glucocerebrosidase (GA-GCB) ERT Compared With Imiglucerase in Type I Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00553631 - Not yet recruiting
  Gaucher Disease, Type 1
  
• A Study of GA-GCB Enzyme Replacement Therapy in Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00430625 - Recruiting
  Gaucher Disease,Type 1
  
• A Study of AT2101 in Patients With Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00446550 - Recruiting
  Gaucher Disease, Type 1
  
• International Collaborative Gaucher Group (ICGG) Gaucher Registry
  ClinicalTrials.gov Identifier: NCT00358943 - Recruiting
  Gaucher Disease; Cerebroside Lipidosis Syndrome; Glucocerebrosidase Deficiency Disease; Glucosylceramide Beta-Glucosidase Deficiency Disease
  
• Convection-Enhanced Delivery of Glucocerebrosidase to Treat Type 2 Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00244582 - Completed
  Type 2 Gaucher Disease
  
• OGT 918-006: A Phase I/II Randomized, Controlled Study of OGT 918 in Patients with Neuronopathic Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00041535 - Active, not recruiting
  Gaucher Disease
  
• A Study to Evaluate and Characterize the Effect of Pharmacological Chemicals on Blood From Patients With Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00465062 - Recruiting
  Gaucher Disease
  
• A Phase III Trial to Assess the Safety and Efficacy of Plant Cell Expressed GCD in Patients With Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00376168 - Recruiting
  Gaucher Disease
  
• Nervous System Degeneration in Glycosphingolipid Storage Disorders
  ClinicalTrials.gov Identifier: NCT00029965 - Recruiting
  Gangliosidoses; Gaucher Disease
  
• Positron Emission Tomography (PET) Imaging in People With Gaucher Mutations
  ClinicalTrials.gov Identifier: NCT00302146 - Recruiting
  Glucocerebrosidase Mutations; Gaucher Disease
  
• Study to Evaluate Blood Cell Lines From Patients With Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00351156 - Completed
  Gaucher Disease
  
• Study on the Prognosis and Effect of Anti-Diabetic Drugs on Type-2 Diabetes Mellitus With Coronary Artery Disease
  ClinicalTrials.gov Identifier: NCT00513630 - Active, not recruiting
  Type 2 Diabetes; Coronary Artery Disease
  
• Phase II Study of Glucocerebrosidase in Patients With Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00004293 - Recruiting
  Gaucher's Disease
  
• Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Efficacy and Pharmacokinetics of Myozyme in Patients with Late-Onset Pompe Disease.
  ClinicalTrials.gov Identifier: NCT00158600 - Active, not recruiting
  Pompe Disease (Late-onset); Glycogen storage disease type II (GSD-II); Acid Maltase Deficiency Disease; Glycogenosis 2
  
• Markers and Mechanisms of Vascular Disease in Type II Diabetes
  ClinicalTrials.gov Identifier: NCT00256646 - Active, not recruiting
  Type 2 Diabetes Mellitus
  
• Blood Pressure and Glucose Lowering for the Prevention of Vascular Disease in High Risk Patients with Type 2 Diabetes.
  ClinicalTrials.gov Identifier: NCT00145925 - Active, not recruiting
  Diabetes Mellitus, Type 2
  
• Post-Marketing Safety Study of GSK Biological''s Pediarix™ Vaccine.
  ClinicalTrials.gov Identifier: NCT00146835 - Active, not recruiting
  Prophylaxis: Diphtheria, tetanus, pertussis, hepatitis B, poliovirus type 1, type 2 and type 3
  
• Efficacy and Safety In Poorly Controlled Type 2 Diabetics
  ClinicalTrials.gov Identifier: NCT00044460 - Active, not recruiting
  type 2 diabetes
  
• Japanese Primary prevention of atherosclerosis with Aspirin for Diabetes (JPAD) Trial
  ClinicalTrials.gov Identifier: NCT00110448 - Active, not recruiting
  Coronary Disease; Arteriosclerosis; Diabetes Mellitus, Type 2
  
• Sulodexide to Treat Type 2 Diabetic Nephropathy
  ClinicalTrials.gov Identifier: NCT00342238 - Recruiting
  Overt Type 2 Diabetic Nephropathy; Chronic Kidney Disease; Diabetes Type 2
  
• Miglustat in Niemann-Pick Type C Disease
  ClinicalTrials.gov Identifier: NCT00517153 - Active, not recruiting
  Niemann-Pick Type C Disease
  
• An Observational Study Evaluating SYMLIN® (Pramlintide Acetate) Injection Use in Insulin Using Patients With Type 2 and Type 1 Diabetes
  ClinicalTrials.gov Identifier: NCT00229658 - Active, not recruiting
  Type 1 Diabetes Mellitus; Type 2 Diabetes Mellitus
  
• Aliskiren Trial in Type 2 Diabetes Using Cardiovascular and Renal Disease Endpoints
  ClinicalTrials.gov Identifier: NCT00549757 - Recruiting
  Type 2 Diabetes Mellitus; Cardiovascular Disease
  
• Evaluation of ALT-2074 in Subjects With Type-2 Diabetes, Haptoglobin Type 2-2 Genotype and Coronary Artery Disease
  ClinicalTrials.gov Identifier: NCT00491543 - Recruiting
  Diabetes; Coronary Artery Disease
  
• Rasagiline 1 mg and 2 mg Added to Aricept 10 mg Daily in Patients with Mild to Moderate Alzheimer's Disease (AD)
  ClinicalTrials.gov Identifier: NCT00104273 - Active, not recruiting
  Dementia, Alzheimer Type
  
• Effects of a Mediterranean Style Diet on Vascular Health in Type 2 Diabetes
  ClinicalTrials.gov Identifier: NCT00163683 - Recruiting
  Type 2 Diabetes; Coronary Heart Disease
  
• Effect of Nuts vs. a Wheat Bran Muffin in Type 2 Diabetes
  ClinicalTrials.gov Identifier: NCT00410722 - Recruiting
  Type 2 Diabetes; Cardiovascular Disease; Diet Therapy
  
• Long-Term Study of Safety and Efficacy of WelChol® as an Additional Therapy in Patients with Type 2 Diabetes
  ClinicalTrials.gov Identifier: NCT00151762 - Active, not recruiting
  Type 2 Diabetes
  
• Islet Transplantation in Type 1 Diabetics Using the Edmonton Protocol of Steroid Free Immunosuppression
  ClinicalTrials.gov Identifier: NCT00133809 - Active, not recruiting
  Diabetes Mellitus, Type 1
  
• PEG-Glucocerebrosidase for the Treatment of Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00001410 - Completed
  Gaucher's Disease
  
• Safety and Immunogenicity Study of Hib-MenCY-TT Vaccine Compared to Licensed Hib and Meningococcal Serogroup C Conjugate Vaccines, Each Administered at 2, 4, 6, and 12 to 15 Months of Age.
  ClinicalTrials.gov Identifier: NCT00134719 - Active, not recruiting
  Invasive bacterial disease caused by Haemophilus influenzae type b and Neisseria meningitidis serogroups C and Y.
  
• Safety of Inhaled Insulin With Type 1 and Type 2 Diabetes
  ClinicalTrials.gov Identifier: NCT00308737 - Active, not recruiting
  Diabetes Mellitus, Type I; Diabetes Mellitus, Type II
  
• A Study to Evaluate the Effects of Pharmacological Chaperones in Cells From Patients With Pompe Disease
  ClinicalTrials.gov Identifier: NCT00515398 - Recruiting
  Pompe Disease; Glycogen Storage Disease Type II
  
• Olmesartan Medoxomil in Diabetes Mellitus
  ClinicalTrials.gov Identifier: NCT00185159 - Active, not recruiting
  Diabetes Mellitus, Type 2; Cardiovascular Disease; Kidney Disease
  
• Efficacy of Alphanate FVIII/VWF Concentrate in Type 3 Von Willebrand Patients
  ClinicalTrials.gov Identifier: NCT00555555 - Recruiting
  Congenital Type 3 Von Willebrand Disease
  
• Late-Onset Treatment Study Extension Protocol
  ClinicalTrials.gov Identifier: NCT00455195 - Active, not recruiting
  Pompe Disease (Late-Onset); Glycogen Storage Disease Type II (GSD-II); Glycogenesis 2; Acid Maltase Deficiency
  
• TRx0014 in Patients With Mild or Moderate Alzheimer's Disease
  ClinicalTrials.gov Identifier: NCT00515333 - Active, not recruiting
  Dementia, Alzheimer Type
  
• A Single-Blind, Placebo-Controlled, Dose-Ranging Trial of Oral HDV-Insulin in Patients With Type 2 Diabetes Mellitus
  ClinicalTrials.gov Identifier: NCT00521378 - Active, not recruiting
  Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2
  
• Glycemic Control and Complications in Diabetes Mellitus Type 2 (VADT)
  ClinicalTrials.gov Identifier: NCT00032487 - Active, not recruiting
  Type 2 diabetes mellitus
  
• ORIENT: Olmesartan Reducing Incidence of End Stage Renal Disease in Diabetic Nephropathy Trial
  ClinicalTrials.gov Identifier: NCT00141453 - Active, not recruiting
  Diabetic Nephropathy; type 2 diabeted mellitus; Proteinuria
  
• Effects of Vitamin B1 in Type 1 Diabetic Patients
  ClinicalTrials.gov Identifier: NCT00117026 - Active, not recruiting
  Diabetes Mellitus, Type 1
  
• Pompe Disease Registry
  ClinicalTrials.gov Identifier: NCT00231400 - Recruiting
  Glycogen Storage Disease Type II; Pompe Disease
  
• Study In People With Type 2 Diabetes
  ClinicalTrials.gov Identifier: NCT00196989 - Active, not recruiting
  Type 2 Diabetes Mellitus
  
• Effect of Metformin in Patients with Type-1 Diabetes with Inadequate Glycaemic Control by Insulin and Diet
  ClinicalTrials.gov Identifier: NCT00118937 - Active, not recruiting
  Diabetes Mellitus, Type 1
  
• Botulinum Toxin Type A (BOTOX) in the Management of Levodopa-Induced Peak-Dose Dyskinesias in Parkinson's Disease
  ClinicalTrials.gov Identifier: NCT00477802 - Recruiting
  Parkinson Disease
  
• Phase I Study of Retrovirally Mediated Transfer of the Human Glucocerebrosidase Gene into Peripheral Blood Stem Cells for Autologous Transplantation in Patients with Type I Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00004294 - Completed
  Gaucher's Disease
  
• Dietary Interventions in Type 2 Obese Diabetic Patients in the Community
  ClinicalTrials.gov Identifier: NCT00520182 - Active, not recruiting
  Diabetes Type 2
  
• Influence of Physical Training on Mitochondrial Function in Type 2 Diabetic Patients
  ClinicalTrials.gov Identifier: NCT00365495 - Active, not recruiting
  Type 2 Diabetes
  
• A Study in Type 1 Diabetic Patients With Repeated Doses of E1 in Combination With G1
  ClinicalTrials.gov Identifier: NCT00239148 - Active, not recruiting
  Type 1 Diabetes
  
• A Study in Type 2 Diabetic Patients With Repeated Doses of E1 in Combination With G1
  ClinicalTrials.gov Identifier: NCT00239187 - Active, not recruiting
  Type 2 Diabetes
  
• Open Trial of Miglitol in Type 2 Diabetic Patients Treated With Biguanide
  ClinicalTrials.gov Identifier: NCT00334503 - Active, not recruiting
  Type 2 Diabetes Mellitus
  
• 4 Weeks Treatment of Type II Diabetic Patients With BI 44847
  ClinicalTrials.gov Identifier: NCT00558909 - Active, not recruiting
  Diabetes Mellitus, Type 2
  
• Surgical Treatment of Non-Obese Type 2 Diabetic Patients With Duodenal Exclusion
  ClinicalTrials.gov Identifier: NCT00566358 - Active, not recruiting
  Diabetes Mellitus, Type 2
  
• Double-Blind Trial of Miglitol in Type 2 Diabetic Patients Treated With Biguanide
  ClinicalTrials.gov Identifier: NCT00334399 - Active, not recruiting
  Type 2 Diabetes Mellitus
  
• Safety and Efficacy of PEG-Encapsulated Islet Allografts Implanted in Type I Diabetic Recipients
  ClinicalTrials.gov Identifier: NCT00260234 - Active, not recruiting
  Diabetes Mellitus, Type 1
  
• Islet Transplantation in Type 1 Diabetic Patients Using the Edmonton Protocol of Steroid Free Immunosuppression
  ClinicalTrials.gov Identifier: NCT00566813 - Active, not recruiting
  Diabetes Mellitus, Type 1
  
• Family Management of Type 1 Diabetes in Children
  ClinicalTrials.gov Identifier: NCT00273286 - Active, not recruiting
  Diabetes Mellitus, Type 1
  
• Sitagliptin vs Glipizide in Patients With Type 2 Diabetes Mellitus and End-Stage Renal Disease
  ClinicalTrials.gov Identifier: NCT00509236 - Recruiting
  Type 2 Diabetes Mellitus; Renal Disease, End-Stage
  
• Phase I Single Dose-Escalation Safety Study of Human Glucocerebrosidase (prGCD)
  ClinicalTrials.gov Identifier: NCT00258778 - Completed
  Gaucher Disease
  
• Lifestyle Intervention in a General Population for Prevention of Ischaemic Heart Disease
  ClinicalTrials.gov Identifier: NCT00289237 - Active, not recruiting
  CHD; AMI; CVD; Type 2 Diabetes; COLD
  
• A 2 Year Random Control Trial of Patients with Type 2 Diabetes Focusing on Cardiovascular Diagnostics and Metabolic Control
  ClinicalTrials.gov Identifier: NCT00133718 - Active, not recruiting
  Diabetes Mellitus; Type 2 Diabetes Mellitus
  
• Effect of Repaglinide Versus Metformin Treatment in Non-Obese Patients With Type-2-Diabetes
  ClinicalTrials.gov Identifier: NCT00118963 - Active, not recruiting
  Diabetes Mellitus, Type 2
  
• Efficacy and Safety of Vildagliptin in Patients with Type 2 Diabetes
  ClinicalTrials.gov Identifier: NCT00102388 - Active, not recruiting
  Diabetes Mellitus, Type 2
  
• Efficacy and Safety of Vildagliptin in Patients with Type 2 Diabetes
  ClinicalTrials.gov Identifier: NCT00106340 - Active, not recruiting
  Diabetes Mellitus, Type 2
  
• Evaluation of Biochemical Markers and Clinical Investigation of Niemann-Pick Disease, Type C
  ClinicalTrials.gov Identifier: NCT00344331 - Recruiting
  Neimann-Pick Disease
  
• New Onset of Type 1 Diabetes Mycophenolate Mofetil-Daclizumab Clinical Trial
  ClinicalTrials.gov Identifier: NCT00100178 - Active, not recruiting
  Diabetes Mellitus, Type 1
  
• Prevalence of Macrovascular Disease in Type 2 Diabetes Mellitus
  ClinicalTrials.gov Identifier: NCT00298844 - Recruiting
  Type 2 Diabetes Mellitus
  
• Diet, Obesity and Genes (DiOGenes)
  ClinicalTrials.gov Identifier: NCT00390637 - Active, not recruiting
  Obesity; Metabolic Syndrome; Type 2 Diabetes; Cardiovascular Disease
  
• Long-term Study of Starlix+Diovan to Delay Type II Diabetes Mellitus
  ClinicalTrials.gov Identifier: NCT00097786 - Active, not recruiting
  Diabetes Mellitus, Type 2
  
• Insulin NovoRapid Vs. Actrapid in Treatment of Type 1 Diabetic Patients During Daily Adjustment of Insulin Dose
  ClinicalTrials.gov Identifier: NCT00145353 - Active, not recruiting
  Type 1 diabetes mellitus
  
• Pilot Study of B-Type Natrieutic Peptide (BNP) Levels in Patients With Congenital Heart Disease(BNP)
  ClinicalTrials.gov Identifier: NCT00308230 - Recruiting
  Congenital Heart Disease; Cardiovascular Disease
  
• A Randomized, Controlled Study on Ca Blocker Vs. AII Antagonists in Hypertension with Type 2 Diabetes
  ClinicalTrials.gov Identifier: NCT00144144 - Active, not recruiting
  Hypertension; Diabetes Mellitus, Type 2
  
• The DURABLE Trial: Evaluating the Durability of Starter Insulin Regimens in Patients With Type 2 Diabetes
  ClinicalTrials.gov Identifier: NCT00279201 - Active, not recruiting
  Diabetes Mellitus, Type 2
  
• Safety of Insulin Detemir Produced by a New Process as Measured by Antibody Formation in Type 1 Diabetes
  ClinicalTrials.gov Identifier: NCT00447382 - Active, not recruiting
  Diabetes Mellitus, Type 1
  
• Effect of Long Term α-Lipoic Acid Treatment on Endothelial Function in Patients With Type 2 Diabetes
  ClinicalTrials.gov Identifier: NCT00490867 - Active, not recruiting
  Type 2 Diabetes
  
• Outcomes and Cost Consequences of Using an Internet Co-Management Module to Improve the Quality of Type 1 Diabetes Care
  ClinicalTrials.gov Identifier: NCT00194558 - Active, not recruiting
  Diabetes Mellitus, Type 1
  
• Study of Weight Loss Using Gastric Stimulation in Obese Patients With Type 2 Diabetes
  ClinicalTrials.gov Identifier: NCT00200018 - Active, not recruiting
  Severe to Morbid Obesity and Type 2 Diabetes
  
• Placebo-Controlled Study of the Combination of SYR-322 and Pioglitazone HCl in the Treatment of Type 2 Diabetes
  ClinicalTrials.gov Identifier: NCT00328627 - Active, not recruiting
  Type 2 Diabetes Mellitus
  
• Efficacy of Vildagliptin 100 MG as Compared to Placebo as Add-on to Metformin in Patients With Type 2 Diabetes
  ClinicalTrials.gov Identifier: NCT00351884 - Active, not recruiting
  Diabetes Mellitus, Type 2
  
• Effect of Liraglutide in Combination With Sulfonylurea (SU) on Blood Glucose Control in Subjects With Type 2 Diabetes
  ClinicalTrials.gov Identifier: NCT00395746 - Active, not recruiting
  Diabetes Mellitus, Type 2
  
• Natural History Study of Plexiform Neurofibromas in Patients With Neurofibromatosis Type 1
  ClinicalTrials.gov Identifier: NCT00445991 - Active, not recruiting
  Neurofibromatosis Type 1 (nf1); Precancerous/Nonmalignant Condition
  
• Safety and Efficacy of Inhaled Pre-Prandial Human Insulin in Type 2 Diabetes
  ClinicalTrials.gov Identifier: NCT00343980 - Active, not recruiting
  Diabetes Mellitus, Type 2
  
• Randomized Study of Real-Time Continuous Glucose Monitors in the Management of Type 1 Diabetes
  ClinicalTrials.gov Identifier: NCT00406133 - Active, not recruiting
  Type 1 Diabetes
  
• Impact of Self-Monitoring Blood Glucose Frequency on Glycemic Control in Patients With Type 2 Diabetes
  ClinicalTrials.gov Identifier: NCT00202033 - Active, not recruiting
  Type 2 Diabetes
  
• A Study Assessing Saxagliptin Treatment in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise
  ClinicalTrials.gov Identifier: NCT00374907 - Active, not recruiting
  Type 2 Diabetes
  
• Drug Interactions From Simultaneous Administration Of Metformin And GSK189075 To Subjects With Type 2 Diabetes
  ClinicalTrials.gov Identifier: NCT00376038 - Active, not recruiting
  Type 2 Diabetes Mellitus
  
• Long Term Safety of Vildagliptin (100mg qd) In Patients With Type 2 Diabetes
  ClinicalTrials.gov Identifier: NCT00389415 - Active, not recruiting
  Diabetes Mellitus, Type 2
  
• A Titration Study of a GLP-1 Analogue in Patients With Type 2 Diabetes Treated With Metformin.
  ClinicalTrials.gov Identifier: NCT00460941 - Active, not recruiting
  Diabetes Mellitus, Type 2
  
• Effect of Real Time Continuous Glucose Monitoring System on the Management of Type 2 Diabetes
  ClinicalTrials.gov Identifier: NCT00536549 - Active, not recruiting
  Type 2 Diabetes
  
• Duration of The Honeymoon Phase of Type 1 Diabetes: A Comparison of Insulins Detemir, Glargine and NPH
  ClinicalTrials.gov Identifier: NCT00564018 - Enrolling by invitation
  Type 1 Diabetes
  
• Efficacy and Safety of Vildagliptin Compared to Placebo on the Incretin Effect in Patients With Type 2 Diabetes Treated With Metformin
  ClinicalTrials.gov Identifier: NCT00396071 - Active, not recruiting
  Diabetes Mellitus, Type 2
  
• Effect of Liraglutide or Exenatide Added to an Ongoing Treatment on Blood Glucose Control in Subjects With Type 2 Diabetes
  ClinicalTrials.gov Identifier: NCT00518882 - Active, not recruiting
  Type 2 Diabetes Mellitus
  
• A Concordance Study Comparing Insulin Treatments in Patients With Type 2 Diabetes
  ClinicalTrials.gov Identifier: NCT00330473 - Active, not recruiting
  Type 2 Diabetes Mellitus