Fabry disease is an inherited disorder caused by the buildup of a particular type of fat (lipid) in the body's cells. This buildup results in pain, particularly in the hands and feet; clusters of small, dark red spots (angiokeratomas) on the skin; a decreased ability to sweat (hypohidrosis); cloudiness of the front part of the eye (the cornea); and hearing loss. Fabry disease also involves potentially life-threatening complications such as progressive kidney damage, heart attack, and stroke. Milder forms of the disorder may appear later in life and affect the heart or kidneys only.