Cri-du-chat syndrome

5p Deletion Syndrome; 5p- Syndrome; Cat cry syndrome

Cri du chat syndrome, also called deletion 5p syndrome, or 5p minus, is a rare genetic disorder due to a missing portion of chromosome 5. It was first described by Jérôme Lejeune in 1963. The condition affects an estimated 1 in 20,000 to 50,000 live births. The disorder is found in people of all ethnic backgrounds and is slightly more common in females. Signs and symptoms Its name, meaning cry of the cat in French, is from the distinctive mewing sound made by infants with the disorder. ...