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Charcot-Marie-Tooth Disease |
AR-CMT2; Charcot-Marie-Tooth disease, type 1; Charcot-Marie-Tooth disease, type 2; Charcot-Marie-Tooth disease, type 4; Charcot-Marie-Tooth Disorder; congenital hypomyelination; Dejerine-Sottas syndrome; DSN; DSS; hereditary motor and sensory neuropathy; HMSN; Peroneal Muscular Atrophy; PMA; Roussy-Levy Syndrome |
Charcot-Marie-Tooth disorder (CMT) is an inherited neurological disease characterized by a slowly progressive degeneration of the muscles in the foot, lower leg, hand, and forearm, and a mild loss of sensation in the limbs, fingers, and toes. The first sign of CMT is generally a high arched foot or gait disturbances. Other symptoms of the disorder may include foot bone abnormalities such as high arches and hammer toes, problems with hand function and balance, occasional lower leg and forearm muscle cramping, loss of some normal reflexes, occasional partial sight and/or hearing loss, and, in some patients, scoliosis (curvature of the spine). CMT is a disorder of genetic heterogeneity, in which mutations in different genes can produce the same clinical symptoms. In CMT, there are not only different genes but different patterns of inheritance.
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Charcot-Marie-Tooth Disease Symptoms1-2 of 4 more...
Signs and symptoms
... The signs and symptoms of CMT may vary from mild to severe and tend to develop slowly, sometimes appearing to stabilize spontaneously. Early signs and symptoms of CMT may include: Weakness in your low...
Source: MayoClinic
Causes ... CMT disease is a general term for a group of inherited diseases involving a defective gene (mutation). The cause of each form of CMT is a mutation particular to that type of the disease. Genes produce...
Source: MayoClinic
Charcot-Marie-Tooth Disease Treatment1-2 of 3 more...
Complications
... Complications of CMT vary in severity from person to person, with foot abnormalities and difficulty walking generally being the most serious problems. Muscle weakness may increase, and injury to areas...
Source: MayoClinic
Treatment ... There''s no cure for CMT. However, some treatments can help you manage its signs and symptoms, including: Physical therapy. Physical therapy for CMT involves muscle strengthening and stretching to pre...
Source: MayoClinic
Charcot-Marie-Tooth Disease Support1 of 1
Coping skills
... Support groups can be valuable in dealing with CMT. They bring together people, family and friends who are coping with the same kind of physical or mental health challenge. Support groups provide a se...
Source: MayoClinic
Charcot-Marie-Tooth Disease Other1-2 of 10 more...
Overview
... Charcot-Marie-Tooth (CMT) disease broadly includes a group of progressive hereditary disorders that cause nerve damage (neuropathy). The damage in CMT occurs to your peripheral nerves or to the insula...
Source: MayoClinic
Charcot-Marie-Tooth Disorder ... What is Charcot-Marie-Tooth disease Charcot-Marie-Tooth disease (CMT) is one of the most common inherited neurological disorders, affecting approximately 1 in 2,500 people in the United States. The di...
Source: Cleveland Clinic
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Charcot-Marie-Tooth Disease Articles
- Charcot-Marie-Tooth disease
... Charcot-Marie-Tooth disease is a group of progressive disorders affecting peripheral nerves. These nerves connect the brain and spinal cord to muscles as well as sensory cells that detect sensations s... - Charcot-Marie-Tooth Disorder Fact Sheet
... Charcot-Marie-Tooth disease (CMT) is one of the most common inherited neurological disorders, affecting approximately 1 in 2,500 people in the United States. The disease is named for the three physici... - Charcot-Marie-Tooth Disorder Information Page
... Charcot-Marie-Tooth disorder (CMT) is an inherited neurological disease characterized by a slowly progressive degeneration of the muscles in the foot, lower leg, hand, and forearm, and a mild loss of ... - Peripheral Neuropathy Fact Sheet
... Peripheral neuropathy describes damage to the peripheral nervous system, the vast communications network that transmits information from the brain and spinal cord (the central nervous system) to every...
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