Neonatal hemochromatosis is a rare iron storage disorder with onset beginning before birth. As with other types of hemochromatosis, excess iron is deposited in the liver, pancreas, heart, endocrine glands, and other tissues. Neonatal hemochromatosis progresses rapidly and is characterized by liver damage that is apparent at birth or in the first day of life. Hemochromatosis, neonatal is a subtype of hemochromatosis. Infants with neonatal hemochromatosis often are stillborn, premature, or born smaller than other full-term infants. End-stage liver disease is generally apparent at birth, even in premature infants. Features of liver failure include low blood sugar, yellowing of the eyes and skin (jaundice), blood clotting disorders, a low number of red blood cells (anemia), and accumulation of fluid (ascites) in the abdomen.