Pantothenate kinase-associated neurodegeneration

NBIA1; Neurodegeneration with Brain Iron Accumulation Type 1; PKAN

Pantothenate kinase-associated neurodegeneration (PKAN) is a form of neurogeneration. Symptoms Pantothenate kinase-associated neurodegeneration (PKAN) is one of many forms of neurodegeneration, or brain deterioration . Neurodegeneration in PKAN is accompanied by an excess of iron that progressively builds in the brain (also called brain iron accumulation or NBIA, formerly called Hallervorden-Spatz syndrome). Symptoms of PKAN begin before middle childhood, and most often are noticed befo ...