Restless Leg Syndrome Clinical Trials

• Relationship Between Sensory and Motor Systems in Restless Leg Syndrome
  ClinicalTrials.gov Identifier: NCT00074672 - Active, not recruiting
  Restless Legs Syndrome
  
• A MULTI-CENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, FIVE-ARM PARALLEL-GROUP TRIAL TO INVESTIGATE THE EFFICACYAND SAFETY OF FOUR DIFFERENT TRANSDERMAL DOSES OF ROTIGOTINE IN SUBJECTS WITH IDIOPATHIC RESTLESS LEGS SYNDROME
  ClinicalTrials.gov Identifier: NCT00135993 - Completed
  Idiopathic Restless Leg syndrome
  
• Rotigotine Restless Legs Syndrome Dose Finding Trial
  ClinicalTrials.gov Identifier: NCT00243217 - Completed
  Idiopathic Restless Leg Syndrome
  
• Swiss Restless Legs Syndrome Trial (SRLS)
  ClinicalTrials.gov Identifier: NCT00144209 - Active, not recruiting
  Restless Legs Syndrome
  
• An Extension Trial to Investigate Long-Term Treatment With Transdermal Rotigotine in Idiopathic Restless Legs Syndrome
  ClinicalTrials.gov Identifier: NCT00263068 - Active, not recruiting
  Restless Legs Syndrome
  
• Non-Interventional Observational Study of Pramipexole in Restless Legs Syndrome: Impact on Quality of Life
  ClinicalTrials.gov Identifier: NCT00539461 - Active, not recruiting
  Restless Legs Syndrome
  
• Long-Term Study of XP13512 vs. Placebo in Patients With Restless Legs Syndrome
  ClinicalTrials.gov Identifier: NCT00311363 - Active, not recruiting
  Restless Legs Syndrome
  
• Transdermal Lisuride: a Trial for the Treatment of Patients With Restless Legs Syndrome (RLS)
  ClinicalTrials.gov Identifier: NCT00367822 - Active, not recruiting
  Restless Legs Syndrome
  
• A Study To Look At The Starting Dose Of Ropinirole Immediate Release Tablets In Young Patients With Restless Legs Syndrome
  ClinicalTrials.gov Identifier: NCT00140712 - Recruiting
  Restless Legs Syndrome
  
• Cross-Sectional Study: Prevalence of Restless Legs Syndrome in Patients With Unpleasant Sensations of the Legs
  ClinicalTrials.gov Identifier: NCT00557258 - Active, not recruiting
  Restless Legs Syndrome
  
• Restless Legs Syndrome Exercise Intervention
  ClinicalTrials.gov Identifier: NCT00258492 - Active, not recruiting
  Restless Legs Syndrome; Insomnia; Daytime Sleepiness
  
• XP13512 vs. Placebo in Patients With Restless Legs Syndrome
  ClinicalTrials.gov Identifier: NCT00365352 - Active, not recruiting
  Restless Legs Syndrome
  
• Long-Term Safety Of Ropinirole XR In Patients With Restless Legs Syndrome
  ClinicalTrials.gov Identifier: NCT00355641 - Recruiting
  Restless Legs Syndrome
  
• Long-Term Study Of Ropinirole In Restless Legs Syndrome
  ClinicalTrials.gov Identifier: NCT00329602 - Recruiting
  Restless Legs Syndrome
  
• XP13512 Extension Study in Patients With Restless Legs Syndrome
  ClinicalTrials.gov Identifier: NCT00333359 - Recruiting
  Restless Legs Syndrome
  
• Clinical Evaluation of Ropinirole CR-RLS ( SK&F106064)Tablets in Restless Legs Syndrome
  ClinicalTrials.gov Identifier: NCT00530790 - Not yet recruiting
  Restless Legs Syndrome
  
• Botulinum Toxin to Treat Restless Legs Syndrome
  ClinicalTrials.gov Identifier: NCT00479154 - Recruiting
  Restless Legs Syndrome
  
• ASP8825 - Study in Patients With Restless Legs Syndrome
  ClinicalTrials.gov Identifier: NCT00530530 - Recruiting
  Restless Legs Syndrome
  
• The Effects Of Ropinirole On Mood Or Mild Depression In Patients With Moderate To Severe Restless Legs Syndrome
  ClinicalTrials.gov Identifier: NCT00357097 - Recruiting
  Moderate to Severe Idiopathic Restless Legs Syndrome (RLS)
  
• SWITCH:Restless Legs Patients Switched to Ropinirole From Pramipexole
  ClinicalTrials.gov Identifier: NCT00344994 - Recruiting
  Restless Legs Syndrome
  
• A Randomized, Double-Blind, Placebo-Controlled Trial with 0.75mg Pramipexole (BI•Sifrol®) Orally Once Daily to Investigate the Efficacy and Safety for 6 Weeks in Patients with Primary Restless Legs Syndrome.
  ClinicalTrials.gov Identifier: NCT00152997 - Completed
  Restless Legs Syndrome
  
• A Double-Blind, Placebo-Controlled, Randomised Withdrawal Study of 3 Month Duration in Patients Suffering from Idiopathic Restless Legs Syndrome Who Responded to a Preceding, 6-Month Treatment with Open-Label Pramipexole Including Titration (0.125, 0.25,
  ClinicalTrials.gov Identifier: NCT00152958 - Completed
  Restless Legs Syndrome
  
• Effect of Ropinirole on Spinal Cord Reflexes and Restless Legs Syndrome
  ClinicalTrials.gov Identifier: NCT00051961 - Completed
  Restless Legs Syndrome
  
• A Sleep Lab Trial to Investigate the Efficacy and Safety of Transdermal Rotigotine in Subjects With Idiopathic Restless Legs Syndrome
  ClinicalTrials.gov Identifier: NCT00275236 - Completed
  Restless Legs Syndrome
  
• A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Clinical Trial Comparing Fixed Doses of 0.25 Mg, 0.50 Mg and 0.75 Mg Pramipexole (Mirapex®) Administered Orally to Investigate the Safety and Efficacy in Patients with Idiopathic Restless
  ClinicalTrials.gov Identifier: NCT00133198 - Completed
  Restless Legs Syndrome
  
• A Double Blind Crossover Trial of Levetiracetam (Keppra®) and Placebo in the Treatment of Restless Legs Syndrome (RLS)
  ClinicalTrials.gov Identifier: NCT00247364 - Completed
  Restless Legs Syndrome
  
• Efficacy and Safety of PPX (Pramipexole) in Moderate to Severe Idiopathic Restless Legs Syndrome (RLS) Patients
  ClinicalTrials.gov Identifier: NCT00275457 - Completed
  Restless Legs Syndrome
  
• Dose Finding Study of Pramipexole (Sifrol) in Patients With Idiopathic Restless Legs Syndrome (RLS).
  ClinicalTrials.gov Identifier: NCT00239486 - Completed
  Restless Legs Syndrome
  
• Study of Istradefylline (KW-6002) for the Treatment of Restless Legs Syndrome
  ClinicalTrials.gov Identifier: NCT00199446 - Completed
  Sleep Disorder; Restless Legs Syndrome
  
• A Clinical Research Study Evaluating Ropinirole Treatment For Restless Legs Syndrome (RLS)
  ClinicalTrials.gov Identifier: NCT00225862 - Completed
  Restless Legs Syndrome
  
• A Clinical Research Study Testing Ropinirole Treatment for Restless Legs Syndrome
  ClinicalTrials.gov Identifier: NCT00363857 - Completed
  Restless Legs Syndrome
  
• Ropinirole XR (Extended Release) In Patients With Restless Legs Syndrome
  ClinicalTrials.gov Identifier: NCT00197080 - Completed
  Restless Legs Syndrome
  
• Efficacy and Safety Study of Topiramate to Treat Restless Legs Syndrome
  ClinicalTrials.gov Identifier: NCT00200941 - Completed
  Restless Legs Syndrome
  
• A Randomised, Comparing Fixed Doses of Pramipexole to Investigate the Efficacy and Safety in Patients With RLS.
  ClinicalTrials.gov Identifier: NCT00390689 - Active, not recruiting
  Restless Legs Syndrome
  
• XP13512 Versus Placebo in Patients With Restless Legs Syndrome
  ClinicalTrials.gov Identifier: NCT00298623 - Completed
  Restless Legs Syndrome
  
• Sequential Compression Devices for Treatment of Restless Legs Syndrome
  ClinicalTrials.gov Identifier: NCT00479531 - Completed
  Restless Legs Syndrome
  
• Phase 3 Open-Label Extension Trial With Rotigotine in Idiopathic Restless Legs Syndrome Subjects
  ClinicalTrials.gov Identifier: NCT00498108 - Completed
  Idiopathic Restless Legs Syndrome
  
• A 6 Week Trial to Study the Efficacy and Safety of a Starting Dose 0.25 mg Pramipexole (Mirapex) in Patients With RLS
  ClinicalTrials.gov Identifier: NCT00375284 - Active, not recruiting
  Restless Legs Syndrome
  
• Long-Term Open-Label Trial in Idiopathic RLS Subjects
  ClinicalTrials.gov Identifier: NCT00498186 - Active, not recruiting
  Idiopathic Restless Legs Syndrome
  
• An Initial Evaluation Of The Safety And Activity Of Celaderm(TM) Treatment Regimens In Healing Venous Leg Ulcers
  ClinicalTrials.gov Identifier: NCT00399308 - Active, not recruiting
  Leg Ulcer; Varicose Ulcer
  
• A Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Four-Arm Parallel-Group Trial to Investigate the Efficacy and Safety of Three Different Transdermal Does of Rotigotine in Subjects with Idiopathic Restless Leg Syndrome
  ClinicalTrials.gov Identifier: NCT00136045 - Completed
  Idiopathic RLS
  
• Prevention of Injuries by an Exercise Program – a RCT
  ClinicalTrials.gov Identifier: NCT00348647 - Active, not recruiting
  Patellofemoral Pain Syndrome; Exertional Lower Leg Pain
  
• Restless Legs Patient Study On Absorption, Distribution, Metabolism And Excretion Of Ropinirole And The Effect Of Food
  ClinicalTrials.gov Identifier: NCT00419692 - Completed
  Restless Legs Syndrome
  
• 12-Week Polysomnography Study of Ropinirole Controlled Release for Restless Legs Syndrome
  ClinicalTrials.gov Identifier: NCT00373542 - Completed
  Restless Legs
  
• RLS In Adults: Comparing Immediate Release Formulation With Extended Release Formulation Of Ropinirole
  ClinicalTrials.gov Identifier: NCT00314860 - Active, not recruiting
  Restless Legs Syndrome
  
• Light Therapy in the Treatment of Leg Pain
  ClinicalTrials.gov Identifier: NCT00253981 - Recruiting
  Tibial Fractures; Leg Injuries
  
• Long-Term Efficacy, Safety and Tolerability of Pramipexole in Patients With Idiopathic Moderate to Severe RLS
  ClinicalTrials.gov Identifier: NCT00472199 - Recruiting
  Restless Legs Syndrome
  
• Stem Cell Study for Patients With Leg Ulcer/Gangrene
  ClinicalTrials.gov Identifier: NCT00221143 - Active, not recruiting
  Leg Pain; Ulcer; Gangrene; Ischemia; Peripheral Vascular Diseases
  
• Safety and Efficacy Study of ICXP007 With Compression Bandaging for the Treatment of Non-Infected Venous Leg Ulcers
  ClinicalTrials.gov Identifier: NCT00232973 - Recruiting
  Leg Ulcer
  
• Converting From Ropinirole Immediate Release (IR) To Ropinirole Controlled-Release for RLS (Restless Legs Syndrome)
  ClinicalTrials.gov Identifier: NCT00256854 - Completed
  Restless Legs Syndrome
  
• Full-Leg vs Below-Knee Elastic Stockings for Prevention of the Post-Thrombotic Syndrome
  ClinicalTrials.gov Identifier: NCT00426075 - Recruiting
  Deep Vein Thrombosis
  
• Comprehensive Police Fatigue Management Program
  ClinicalTrials.gov Identifier: NCT00246051 - Not yet recruiting
  Sleep Disorders; Sleep Apnea, Obstructive; Restless Legs Syndrome; Sleep Disorders, Circadian Rhythm; Sleep Initiation and Maintenance Disorders
  
• Legtest Multi Centre Testing of the Lively Legs Program for Promoting Compliance in Leg Ulcer Patients
  ClinicalTrials.gov Identifier: NCT00184873 - Recruiting
  Leg Ulcers; Varicose Ulcers
  
• Study of the Ability of Alfimeprase to Rapidly Dissolve Blood Clots in the Leg and Help Prevent the Need for Surgery on Leg Arteries
  ClinicalTrials.gov Identifier: NCT00115999 - Active, not recruiting
  Arterial Occlusive Diseases
  
• Leg Amputation and Continuous Sciatic Nerve Block
  ClinicalTrials.gov Identifier: NCT00427947 - Recruiting
  Phantom Limb; Leg Amputation
  
• The Efficacy Of The Wavelight Mydon Laser for Hair Removal And Treatment of Leg Veins
  ClinicalTrials.gov Identifier: NCT00366964 - Active, not recruiting
  Leg Veins; Hair Removal
  
• Bioengineered Skin and Wound Healing
  ClinicalTrials.gov Identifier: NCT00007280 - Active, not recruiting
  Leg Ulcers
  
• A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Proof-of-Concept Trial to Assess the Efficacy, Safety and Tolerability of Ascending Doses of Rotigotine Nasal Spray for the Acute Treatment of RLS Symptoms in Subjects With Idiopathic Restless
  ClinicalTrials.gov Identifier: NCT00389831 - Completed
  Idiopathic Restless Legs Syndrome
  
• Continuous Pressure Monitoring In Lower Leg Fractures
  ClinicalTrials.gov Identifier: NCT00358514 - Not yet recruiting
  Compartment Syndrome
  
• RCT to Investigate if Prophylactic Antibiotics Prevent Further Episodes of Cellulitis (Erysipelas) of the Leg
  ClinicalTrials.gov Identifier: NCT00552799 - Recruiting
  Cellulitis/Erysipelas of the Leg
  
• Sleep Disorders Management, Health and Safety in Police
  ClinicalTrials.gov Identifier: NCT00207285 - Recruiting
  Sleep Disorders; Sleep Apnea, Obstructive; Restless Legs Syndrome; Sleep Disorders, Circadian Rhythm; Sleep Initiation and Maintenance Disorders
  
• Changes in Cerebral Blood Flow in Patients Treated With Spinal Cord Stimulation for Low Back and Leg Pain
  ClinicalTrials.gov Identifier: NCT00418301 - Recruiting
  Pain; Low Back Pain; Leg Pain
  
• Chiropractic and Self-Care for Back-Related Leg Pain
  ClinicalTrials.gov Identifier: NCT00494065 - Recruiting
  Sub-Acute and Chronic Back-Related Leg Pain
  
• CLUE Study: Connective Tissue Disease Leg Ulcer Etiology Study
  ClinicalTrials.gov Identifier: NCT00522002 - Recruiting
  Connective Tissue Diseases; Blood Coagulation Disorders; Leg Ulcers; Rheumatoid Arthritis; Systemic Lupus Erythematosus; Systemic Scleroderma; Mixed Connective Tissue Disease
  
• Jugular Vein Sampling for Hormone Levels for the Diagnosis of Cushing Syndrome
  ClinicalTrials.gov Identifier: NCT00001453 - Active, not recruiting
  Cushing's Syndrome
  
• Study of Hypercortisolism in Cushing's Syndrome and Stress-Induced Pseudo-Cushing's Syndrome
  ClinicalTrials.gov Identifier: NCT00004343 - Active, not recruiting
  Cushing's Syndrome
  
• IGF-I/IGFBP-3 Therapy in Children and Adolescents With Growth Hormone Insenitivity Syndrome (GHIS) Such as Laron Syndrome
  ClinicalTrials.gov Identifier: NCT00368173 - Active, not recruiting
  Growth Hormone Insensitivity Syndrome (GHIS); Laron Syndrome
  
• Influence of Leg Length Discrepancy on the Spinal Shape and Biomechanics in Functional and Idiopathic Scoliosis Patients
  ClinicalTrials.gov Identifier: NCT00155545 - Not yet recruiting
  functional scoliosis; idiopathic scoliosis; leg length discrepancy
  
• Amifostine in Treating Patients With Myelodysplastic Syndrome
  ClinicalTrials.gov Identifier: NCT00003048 - Active, not recruiting
  Previously Treated Myelodysplastic Syndrome; secondary myelodysplastic syndrome; de novo myelodysplastic syndrome
  
• Study of Alfimeprase's Ability to Dissolve Blood Clots in the Leg and Help Prevent the Need for Surgery
  ClinicalTrials.gov Identifier: NCT00338585 - Active, not recruiting
  Arterial Occlusive Diseases
  
• Study of Genetic and Molecular Defects in Primary Immunodeficiency Disorders
  ClinicalTrials.gov Identifier: NCT00004341 - Active, not recruiting
  X-linked agammaglobulinemia; X-linked hyper IgM syndrome; Wiskott-Aldrich Syndrome; Leukocyte Adhesion Deficiency Syndrome
  
• Monoclonal Antibody Therapy in Treating Patients With Primary Myelodysplastic Syndrome
  ClinicalTrials.gov Identifier: NCT00003984 - Active, not recruiting
  Previously Treated Myelodysplastic Syndrome; secondary myelodysplastic syndrome; de novo myelodysplastic syndrome; ...
  
• Down Syndrome - Comparison of Screening Methods in the 1st and 2nd Trimesters
  ClinicalTrials.gov Identifier: NCT00006445 - Active, not recruiting
  Down Syndrome; Chromosome Abnormalities
  
• Anti-CD20 Antibody Therapy for Sjogren's Syndrome
  ClinicalTrials.gov Identifier: NCT00101829 - Active, not recruiting
  Sjogren's Syndrome
  
• Vaccine Therapy in Treating Patients With Myelodysplastic Syndrome
  ClinicalTrials.gov Identifier: NCT00003959 - Active, not recruiting
  Refractory Anemia; Previously Treated Myelodysplastic Syndrome; secondary myelodysplastic syndrome; refractory anemia with ringed sideroblasts; ...
  
• Modafinil to Treat Fatigue in Post-Polio Syndrome
  ClinicalTrials.gov Identifier: NCT00067496 - Active, not recruiting
  Postpoliomyelitis Syndrome
  
• Vacuum Suspension: Effects On Tissue Oxygenation, Activity and Fit
  ClinicalTrials.gov Identifier: NCT00117793 - Not yet recruiting
  Amputation; Traumatic Amputations; Diabetes; Leg Injuries
  
• The effect of androgen and growth hormone on height and learning in girls with Turner syndrome
  ClinicalTrials.gov Identifier: NCT00029159 - Active, not recruiting
  Turner Syndrome
  
• The Evaluation of OrCel for the Treatment of Venous Ulcers
  ClinicalTrials.gov Identifier: NCT00270972 - Active, not recruiting
  Venous Insufficiency; Leg Ulcer
  
• Prosthetic Components and Stability in Amputee Gait
  ClinicalTrials.gov Identifier: NCT00167778 - Not yet recruiting
  Amputation; Traumatic Amputation; Diabetes; Leg Injuries
  
• MPS I Registry
  ClinicalTrials.gov Identifier: NCT00144794 - Recruiting
  Mucopolysaccharidosis I; Hurler''s Syndrome; Hurler-Scheie Syndrome; Scheie Syndrome
  
• Amifostine With or Without Epoetin alfa in Treating Patients With Myelodysplastic Syndrome
  ClinicalTrials.gov Identifier: NCT00003681 - Active, not recruiting
  Refractory Anemia; Previously Treated Myelodysplastic Syndrome; Anemia; secondary myelodysplastic syndrome; ...
  
• Evaluating the Occurence of New and Progression of Existing Peripheral Venous Disease in Leg Veins
  ClinicalTrials.gov Identifier: NCT00508079 - Active, not recruiting
  Peripheral Vascular Diseases
  
• Antidepressant Treatment for Premenstrual Syndrome and Premenstrual Dysphoric Disorder
  ClinicalTrials.gov Identifier: NCT00048854 - Active, not recruiting
  Premenstrual Syndrome
  
• Sensing of Leg Position and Movement
  ClinicalTrials.gov Identifier: NCT00100919 - Active, not recruiting
  Proprioception
  
• Detection of Residual Disease in Children Receiving Therapy for Acute Myeloid Leukemia or Myelodysplastic Syndrome
  ClinicalTrials.gov Identifier: NCT00003790 - Active, not recruiting
  Previously Treated Myelodysplastic Syndrome; untreated childhood acute myeloid leukemia; secondary myelodysplastic syndrome; ...
  
• Carperitide in Acute Respiratory Distress Syndrome (ARDS)
  ClinicalTrials.gov Identifier: NCT00030121 - Active, not recruiting
  Respiratory Distress Syndrome
  
• Phase IV Trial With Pramipexole to Evaluate Safety and Efficacy in Patients With RLS Associated With Mood Disturbances
  ClinicalTrials.gov Identifier: NCT00356096 - Completed
  Restless Legs Syndrome; Depression
  
• A Study to Evaluate the Clinical Effectiveness of a Collagen-ORC Antimicrobial Matrix in Venous Leg Ulcers
  ClinicalTrials.gov Identifier: NCT00235209 - Completed
  Leg Ulcer
  
• Genetic Analysis of Birt Hogg-Dube Syndrome and Characterization of Predisposition to Kidney Cancer
  ClinicalTrials.gov Identifier: NCT00033137 - Recruiting
  Syndrome
  
• Manifestations of Heritable Disorders of Connective Tissue
  ClinicalTrials.gov Identifier: NCT00270686 - Recruiting
  Ehlers-Danlos Syndrome; Marfan Syndrome; Stickler Syndrome
  
• Pilot Study of Allogeneic Bone Marrow Transplantation Plus Cyclosporine and Mycophenolate Mofetil to Induce Mixed Hematopoietic Chimerism in Patients With Primary T-Cell Immunodeficiency Disorders
  ClinicalTrials.gov Identifier: NCT00008450 - Recruiting
  Purine-Pyrimidine Metabolism, Inborn Errors; Wiskott-Aldrich Syndrome; Bare Lymphocyte Syndrome; Lymphopenia; Job's Syndrome; DiGeorge Syndrome; ...
  
• Pioglitazone Treatment in Polycystic Ovary Syndrome
  ClinicalTrials.gov Identifier: NCT00145340 - Active, not recruiting
  Polycystic Ovary Syndrome
  
• Down Syndrome and Continuous Positive Pressure Therapy
  ClinicalTrials.gov Identifier: NCT00394290 - Recruiting
  Down Syndrome; Obstructive Sleep Apnea Syndrome
  
• Study of Tics in Patients with Tourette's Syndrome and Chronic Motor Tic Disorder
  ClinicalTrials.gov Identifier: NCT00033995 - Active, not recruiting
  Tourette Syndrome; Tic Disorders
  
• Combination Treatment With Bosentan and Sildenafil to Patients With Eisenmengers Syndrome
  ClinicalTrials.gov Identifier: NCT00303004 - Active, not recruiting
  Eisenmenger Syndrome
  
• Effect of MAXOMAT ® on the Growth of Small Children to NOONAN's Syndrome
  ClinicalTrials.gov Identifier: NCT00452725 - Active, not recruiting
  Noonan Syndrome
  
• Sex Steroids in Sjögren's Syndrome: Effect of Substitution Treatment on Fatigue
  ClinicalTrials.gov Identifier: NCT00543166 - Active, not recruiting
  Sjogren's Syndrome
  
• Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies
  ClinicalTrials.gov Identifier: NCT00006054 - Active, not recruiting
  Immunologic Deficiency Syndromes; Chediak-Higashi Syndrome; Common Variable Immunodeficiency; Graft Versus Host Disease; ...
  
• Vitamin E in Aging Persons With Down Syndrome
  ClinicalTrials.gov Identifier: NCT00056329 - Active, not recruiting
  Down Syndrome; Alzheimer Disease