Not Signed In -
Occupational asthma |
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Clinical Trial: Nutrition in Pregnancy, Birth Weight, and Childhood Asthma
This study is no longer recruiting patients.
Purpose
To evaluate the role of maternal diet and birth weight in the etiology of childhood asthma and other allergic disorders.
| Condition |
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| Lung Diseases Asthma |
MedlinePlus related topics: Asthma; Respiratory Diseases
Study Type: Observational
Study Design: Natural History, Longitudinal, Defined Population
Study start: September 2000; Study completion: July 2005
BACKGROUND: Asthma is one of the most common chronic diseases diagnosed among children in the developed world, and its prevalence in western industrialized countries is increasing at an alarming rate. Little information is currently available regarding the role of maternal diet during pregnancy and birth weight in the risk of childhood asthma.
DESIGN NARRATIVE: This longitudinal prospective study takes advantage of the resources provided by Project Viva, an ongoing prospective cohort study of pregnant women and their infant offspring among members of Harvard Pilgrim Health Care, a large managed care organization in New England. Data already available from Project Viva include detailed dietary data on mother and infant, along with data on anthropometric, social, environmental, demographic, economic, psychological, and lifestyle variables. The study will follow the Project Viva cohort until ages 3 to 4 years.
Eligibility
Genders Eligible for Study: Both
Criteria
Location Information
Matthew Gillman, Harvard Pilgrim Health Care, Inc.
More Information
Publications
Oken E, Kleinman KP, Berland WE, Simon SR, Rich-Edwards JW, Gillman MW. Decline in fish consumption among pregnant women after a national mercury advisory. Obstet Gynecol. 2003 Aug;102(2):346-51.
Oken E, Gillman MW. Fetal origins of obesity. Obes Res. 2003 Apr;11(4):496-506. Review.
Gillman MW. Epidemiological challenges in studying the fetal origins of adult chronic disease. Int J Epidemiol. 2002 Apr;31(2):294-9. Review. No abstract available.
Schroeter CH, Schaub B, Gold DR, Contreras PJ, Manrique O, Gillman MW, Weiss S, Palmer LJ, Perkins D, Finn PW. Nuclear factor kappa B activation in human cord blood mononuclear cells. Pediatr Res. 2004 Aug;56(2):212-8. Epub 2004 Jun 04.
Mone SM, Gillman MW, Miller TL, Herman EH, Lipshultz SE. Effects of environmental exposures on the cardiovascular system: prenatal period through adolescence. Pediatrics. 2004 Apr;113(4 Suppl):1058-69. Review.
Moore MM, Rifas-Shiman SL, Rich-Edwards JW, Kleinman KP, Camargo CA Jr, Gold DR, Weiss ST, Gillman MW. Perinatal predictors of atopic dermatitis occurring in the first six months of life. Pediatrics. 2004 Mar;113(3 Pt 1):468-74.
Gillman MW, Rich-Edwards JW, Rifas-Shiman SL, Lieberman ES, Kleinman KP, Lipshultz SE. Maternal age and other predictors of newborn blood pressure. J Pediatr. 2004 Feb;144(2):240-5.
Taveras EM, Scanlon KS, Birch L, Rifas-Shiman SL, Rich-Edwards JW, Gillman MW. Association of breastfeeding with maternal control of infant feeding at age 1 year. Pediatrics. 2004 Nov;114(5):e577-83. Epub 2004 Oct 18.
Oken E, Kleinman KP, Olsen SF, Rich-Edwards JW, Gillman MW. Associations of seafood and elongated n-3 fatty acid intake with fetal growth and length of gestation: results from a US pregnancy cohort. Am J Epidemiol. 2004 Oct 15;160(8):774-83.
Gillman MW, Rifas-Shiman SL, Kleinman KP, Rich-Edwards JW, Lipshultz SE. Maternal calcium intake and offspring blood pressure. Circulation. 2004 Oct 5;110(14):1990-5. Epub 2004 Sep 27.
Schaub B, Bellou A, Gibbons FK, Velasco G, Campo M, He H, Liang Y, Gillman MW, Gold D, Weiss ST, Perkins DL, Finn PW. TLR2 and TLR4 stimulation differentially induce cytokine secretion in human neonatal, adult, and murine mononuclear cells. J Interferon Cytokine Res. 2004 Sep;24(9):543-52.
Record last reviewed: February 2005
Last Updated: February 17, 2005
Record first received: October 12, 2000
ClinicalTrials.gov Identifier: NCT00006404
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08
Source: ClinicalTrials.gov
Cache Date: April 9, 2005
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