Not Signed In -
Respiratory Infection |
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Clinical Trial: Papilloma Virus Vaccine Therapy in Treating Young Patients With Recurrent Papilloma of the Larynx
This study is no longer recruiting patients.
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Purpose
RATIONALE: Vaccines made from papilloma virus cells may make the body build an immune response to and kill papilloma cells. PURPOSE: Phase II trial to study the effectiveness of papilloma virus vaccine in treating young patients with recurrent papilloma of the larynx.
| Condition | Treatment or Intervention | Phase |
|---|---|---|
| respiratory papillomas | Drug: autologous tumor cell vaccine | Phase II |
MedlinePlus related topics: Cancer; Cancer Alternative Therapy; Respiratory Diseases
Study Type: Interventional
Study Design: Treatment
Official Title: Phase II Immunotherapy With Autogenous Papilloma Vaccine in Patients With Recurrent Juvenile Papilloma of the Larynx
Study start: December 1971
OBJECTIVES: I. Determine the immune response in patients with juvenile papilloma of the larynx treated with autogenous vaccine derived from each patient's own tumor.
PROTOCOL OUTLINE: Patients receive autogenous papilloma vaccine intradermally and subcutaneously weekly for 20 weeks.
PROJECTED ACCRUAL: Not specified
Eligibility
Ages Eligible for Study: 1 Year and above
Criteria
PROTOCOL ENTRY CRITERIA:
--Disease Characteristics--
- Diagnosis of severe recurrent juvenile papilloma of the larynx requiring surgery at least 4 times per year; Condition must have existed for more than 1 year
--Prior/Concurrent Therapy--
- See Disease Characteristics
--Patient Characteristics--
- Age: 1 year and over
- Performance status: Not specified
- Life expectancy: Not specified
- Hematopoietic: Not specified
- Hepatic: Not specified
- Renal: Not specified
Location Information
New Jersey
New Jersey Medical School, Newark, New Jersey, 07103-2714, United States
James M. Oleske, Study Chair, New Jersey Medical School
More Information
Clinical trial summary from the National Cancer Institute's PDQ® database
Publications
Oleske J, Fishman D, Cooper R, et al.: Autogenous vaccine in the treatment of laryngeal papilloma. Proceeding of the 12th International Congress of Chemotherapy 1099-1101, 1981.
Oleske JM, Kushnick T. Juvenile papilloma of the larynx. Am J Dis Child. 1971 May;121(5):417-9. No abstract available.
Record last reviewed: February 2004
Last Updated: October 13, 2004
Record first received: November 1, 1999
ClinicalTrials.gov Identifier: NCT00002454
Health Authority: Unspecified
ClinicalTrials.gov processed this record on 2005-04-08
Source: ClinicalTrials.gov
Cache Date: April 9, 2005
Resources
- Bacterial vs Viral/Respiratory Tract Infections: When Should Antibiotics be Taken? (Cleveland Clinic)
- Respiratory Infection (Cleveland Clinic)
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