Valproic acid Clinical Trials

• Randomized Phase Iii-Study On Valproic Acid In Combination With All-Trans Retinoic Acid, Standard Induction- And Consolidation Therapy In Older Patients With Newly Diagnosed Acute Myeloid Leukemia
  ClinicalTrials.gov Identifier: NCT00151255 - Recruiting
  Acute myeloid leukemia, age > 60 years
  
• Randomized Phase Ii-Study On Valproic Acid, All-Trans Retinoic Acid And Their Combination In Induction And Consolidation Therapy As Well As Pegfilgrastim After Consolidation Therapy In Younger Patients With Newly Diagnosed Acute Myeloid Leukemia
  ClinicalTrials.gov Identifier: NCT00151242 - Recruiting
  Acute Myeloid Leukemia
  
• Valproic Acid in Treating Patients With Kaposi's Sarcoma
  ClinicalTrials.gov Identifier: NCT00075777 - Active, not recruiting
  recurrent Kaposi's sarcoma; epidemic Kaposi's sarcoma
  
• Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors
  ClinicalTrials.gov Identifier: NCT00107458 - Active, not recruiting
  childhood brain tumor; childhood meningioma; childhood solid tumor; childhood spinal cord tumors
  
• PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS
  ClinicalTrials.gov Identifier: NCT00439673 - Active, not recruiting
  Myelodysplastic Syndromes
  
• Decitabine and Valproic Acid in Treating Patients With Non-Small Cell Lung Cancer
  ClinicalTrials.gov Identifier: NCT00084981 - Active, not recruiting
  recurrent non-small cell lung cancer; stage IV non-small cell lung cancer
  
• Azacytidine With Valproic Acid Versus Ara-C in AML/MDS Patients
  ClinicalTrials.gov Identifier: NCT00382590 - Active, not recruiting
  Acute Myelogenous Leukemia; Myelodysplastic Syndrome; Leukemia
  
• Phase I Trial of Valproic Acid and Epirubicin in Solid Tumor Malignancies
  ClinicalTrials.gov Identifier: NCT00246103 - Recruiting
  Neoplams, Advanced
  
• The Effects of Valproic Acid on Zidovudine Glucuronidation and Pharmacokinetics in HIV-Infected Patients.
  ClinicalTrials.gov Identifier: NCT00000629 - Completed
  HIV Infections
  
• Decitabine With or Without Valproic Acid in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
  ClinicalTrials.gov Identifier: NCT00109824 - Recruiting
  recurrent adult Burkitt's lymphoma; recurrent adult diffuse large cell lymphoma; recurrent mantle cell lymphoma
  
• Comparing Compliance, Tolerability, Efficacy and Adverse Events in Bipolar Tients From Valproic Acid to Depakote ER.
  ClinicalTrials.gov Identifier: NCT00211250 - Recruiting
  Mood Disorder
  
• Valproic Acid, Temozolomide, and Radiation Therapy in Treating Patients With Glioblastoma Multiforme
  ClinicalTrials.gov Identifier: NCT00313664 - Recruiting
  Brain and Central Nervous System Tumors
  
• Decitabine and Valproic Acid in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia or Previously Treated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
  ClinicalTrials.gov Identifier: NCT00079378 - Recruiting
  adult acute myeloid leukemia; refractory chronic lymphocytic leukemia; Small Lymphocytic Lymphoma
  
• Study of Valproic Acid to Treat HIV Infected Adults
  ClinicalTrials.gov Identifier: NCT00312546 - Recruiting
  HIV Infections
  
• Phase I/II Trial of Valproic Acid and Karenitecin for Melanoma
  ClinicalTrials.gov Identifier: NCT00358319 - Recruiting
  Malignant Melanoma
  
• Valproic Acid and Its Effects on HIV Latent Reservoirs
  ClinicalTrials.gov Identifier: NCT00289952 - Recruiting
  HIV Infections
  
• Valproic Acid (Depakote ER) in Patients With Advanced Thyroid Cancer
  ClinicalTrials.gov Identifier: NCT00525135 - Recruiting
  Head and Neck Cancer
  
• Valproic Acid-Based 2-Agent Oral Regimens for Patients With Advanced Solid Tumor
  ClinicalTrials.gov Identifier: NCT00495872 - Recruiting
  Advanced Cancer
  
• Azacytidine and Valproic Acid in Patients With Advanced Cancers
  ClinicalTrials.gov Identifier: NCT00496444 - Active, not recruiting
  Advanced Cancers
  
• Phase II Study of Valproic Acid With FEC100 for Patients With Locally Advanced Breast Cancer
  ClinicalTrials.gov Identifier: NCT00437801 - Recruiting
  Breast Cancer
  
• Phase I Study of Temazolomide, Valproic Acid and Radiation Therapy in Subjects With Brain Metastases
  ClinicalTrials.gov Identifier: NCT00437957 - Recruiting
  Unresectable Brain Metastases
  
• Valproic Acid in the Induction of EBV Lytic Cycle Antigen Expression in Nasopharyngeal Carcinoma
  ClinicalTrials.gov Identifier: NCT00181220 - Recruiting
  Nasopharyngeal Carcinoma
  
• Valproic Acid and Carnitine in Patients With Spinal Muscular Atrophy
  ClinicalTrials.gov Identifier: NCT00227266 - Active, not recruiting
  Spinal Muscular Atrophy
  
• 5-Azacytidine Valproic Acid and ATRA in AML and High Risk MDS
  ClinicalTrials.gov Identifier: NCT00339196 - Recruiting
  Acute Myelogenous Leukaemia (AML); Myelodysplastic Syndrome (MDS)
  
• Azacitidine and Valproic Acid Plus Carboplatin in Patients With Platinum Resistant Epithelial Ovarian Cancer
  ClinicalTrials.gov Identifier: NCT00529022 - Recruiting
  Advanced Cancer; Ovarian Cancer
  
• Valproic Acid and Bevacizumab in Patients With Advanced Cancer
  ClinicalTrials.gov Identifier: NCT00530907 - Recruiting
  Advanced Cancer
  
• Randomized Placebo-Controlled Trial of Valproic Acid in Patients With Progressive Supranuclear Palsy
  ClinicalTrials.gov Identifier: NCT00385710 - Recruiting
  Progressive Supranuclear Palsy (PSP)
  
• Valproic Acid in Ambulant Adults With Spinal Muscular Atrophy
  ClinicalTrials.gov Identifier: NCT00481013 - Recruiting
  Spinal Muscular Atrophy
  
• Compliance With Once-Daily Divalproex Extended-Release Tablets (Depakote-ER) Versus Multiple-Daily Dose Valproic Acid Capsules (Depakene) in Epilepsy:
  ClinicalTrials.gov Identifier: NCT00356018 - Not yet recruiting
  Epilepsy
  
• Childhood Absence Epilepsy Rx PK-PD-Pharmacogenetics Study
  ClinicalTrials.gov Identifier: NCT00088452 - Active, not recruiting
  Childhood Absence Epilepsy; Petit Mal Epilepsy; Epilepsy; Seizures
  
• HDAC Inhibitor Valproic Acid as an Effective Therapy for Chronic Lymphocytic Leukemia
  ClinicalTrials.gov Identifier: NCT00524667 - Not yet recruiting
  Chronic Lymphocytic Leukemia
  
• Phase I/II Study of Decitabine and Valproic Acid in Relapsed/Refractory Leukemia or Myelodysplastic Syndromes
  ClinicalTrials.gov Identifier: NCT00075010 - Terminated
  Leukemia; Myelodysplastic Syndromes
  
• Activity of Essential Fatty Acid Elongation/Desaturation Pathway During Early Life in Human Infants, In Vivo
  ClinicalTrials.gov Identifier: NCT00342303 - Active, not recruiting
  Fatty Acid Metabolism
  
• A study to compare the efficacy of intravenous loading doses followed by maintenance treatment with oral ibandronic acid versus zoledronic acid in patients with skeletal metastases experiencing moderate to severe pain.
  ClinicalTrials.gov Identifier: NCT00099177 - Active, not recruiting
  Pain; Bone Neoplasms; Neoplasm Metastasis
  
• A study to compare the efficacy of intravenous loading doses followed by maintenance treatment with intravenous ibandronic acid versus zoledronic acid in patients with skeletal metastases experiencing moderate to severe pain.
  ClinicalTrials.gov Identifier: NCT00099203 - Active, not recruiting
  Pain; Bone Neoplasms; Neoplasm Metastasis
  
• Relationship Between Folic Acid and Warfarin Metabolism and Effect
  ClinicalTrials.gov Identifier: NCT00162409 - Recruiting
  Folic Acid Deficiency
  
• DHA (Docosahexaenoic Acid), an Omega 3 Fatty Acid, in Slowing the Progression of Alzheimer's Disease
  ClinicalTrials.gov Identifier: NCT00440050 - Active, not recruiting
  Alzheimer's Disease
  
• Double-Blind Extension of HORIZON Pivotal Fracture Trial (Zoledronic Acid in the Treatment of Postmenopausal Osteoporosis)
  ClinicalTrials.gov Identifier: NCT00145327 - Active, not recruiting
  Osteoporosis
  
• Folic Acid and Omega -3 Fatty Acid Supplementation in Depressed Older Adults
  ClinicalTrials.gov Identifier: NCT00480207 - Recruiting
  Depression
  
• On-Demand Use of Pantoprazole: Determinants for Chronic Use of Acid Suppressive Medication
  ClinicalTrials.gov Identifier: NCT00161096 - Active, not recruiting
  Chronic Use of Acid Suppressive Medication; GORD; GERD; Reflux; Peptic Ulcer
  
• Valproic Acid Sodium Salt in Bipolar Disorder
  ClinicalTrials.gov Identifier: NCT00431522 - Completed
  Bipolar Disorder
  
• Safety and Efficiency Study of Valproic Acid In HAM/TSP
  ClinicalTrials.gov Identifier: NCT00519181 - Terminated
  HTLV-I-Associated Myelopathy
  
• Study of Safety and Dosing Effect on SMN Levels of Valproic Acid (VPA) in Patients With Spinal Muscular Atrophy
  ClinicalTrials.gov Identifier: NCT00374075 - Completed
  Spinal Muscular Atrophy
  
• Suberoylanilide Hydroxamic Acid in Treating Patients With Advanced Cancer
  ClinicalTrials.gov Identifier: NCT00045006 - Active, not recruiting
  Cancer
  
• Feasibility of Retinoic Acid Treatment in Emphysema (FORTE)
  ClinicalTrials.gov Identifier: NCT00000621 - Active, not recruiting
  Emphysema; Lung Diseases; Lung Diseases, Obstructive; Chronic Obstructive Pulmonary Disease
  
• Effect of Polyunsaturated Fatty Acids on Cardiovascular and Motor Responses Under Stress
  ClinicalTrials.gov Identifier: NCT00014027 - Recruiting
  Healthy
  
• Efficacy and Safety of Zoledronic Acid in the Prevention of Bone Loss in Postmenopausal Women with Osteopenia, 45 Years of Age and Older.
  ClinicalTrials.gov Identifier: NCT00132808 - Active, not recruiting
  Osteopenia (osteoporosis prevention)
  
• Comparison of the Gastric Acid Suppressive Effects of Esomeprazole and Generic Omeprazole
  ClinicalTrials.gov Identifier: NCT00542347 - Recruiting
  Gastric Acid
  
• A Pharmacokinetic Study to Compare the Dosing of Valproic Acid in Subjects With Different Body Weights
  ClinicalTrials.gov Identifier: NCT00298857 - Terminated
  Healthy; Obesity; Pharmacokinetics
  
• The Effect of Folic Acid on Efficacy of Sulfadoxine-Pyrimethamine in Pregnant Women in Western Kenya
  ClinicalTrials.gov Identifier: NCT00130065 - Active, not recruiting
  Malaria
  
• A Study of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients with Solid Tumors
  ClinicalTrials.gov Identifier: NCT00127127 - Active, not recruiting
  Tumors
  
• Controlled Trial of 4-Aminosalicylic Acid in Patients with Small Bowel Crohn's Disease
  ClinicalTrials.gov Identifier: NCT00004423 - Active, not recruiting
  Crohn's Disease
  
• Study of Docosahexaenoic Acid (DHA) Supplementation in Patients with X-Linked Retinitis Pigmentosa
  ClinicalTrials.gov Identifier: NCT00004827 - Active, not recruiting
  Retinitis Pigmentosa
  
• An Investigational Drug Study with Suberoylanilide Hydroxamic Acid in Relapsed Diffuse Large B-cell Lymphoma
  ClinicalTrials.gov Identifier: NCT00097929 - Active, not recruiting
  B-Cell Lymphoma
  
• Asenapine with Lithium or Valproic Acid for Bipolar Disorder (Information Omitted Due to Their Commercial Sensitivity)
  ClinicalTrials.gov Identifier: NCT00145470 - Completed
  Bipolar Disorder
  
• Safety and Efficacy Trial with Zoledronic Acid for the Treatment of Paget's Disease of Bone
  ClinicalTrials.gov Identifier: NCT00103740 - Active, not recruiting
  Paget's Disease of Bone
  
• Randomized Study of Tauroursodeoxycholic Acid in Prophylactic Therapy of Total Parenteral Nutrition Associated Cholestasis in Infants
  ClinicalTrials.gov Identifier: NCT00004410 - Recruiting
  Cholestasis
  
• A Study of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients with Malignant Lymphoma
  ClinicalTrials.gov Identifier: NCT00127140 - Active, not recruiting
  Malignant Lymphoma
  
• Suberoylanilide Hydroxamic Acid in Treating Patients With Relapsed Non-Hodgkin''s Lymphoma
  ClinicalTrials.gov Identifier: NCT00124631 - Active, not recruiting
  recurrent adult diffuse large cell lymphoma
  
• High-Dose Folic Acid in Preventing Colorectal Cancer in Patients Who Have Had Polyps Surgically Removed
  ClinicalTrials.gov Identifier: NCT00002650 - Active, not recruiting
  Rectal Cancer; prevention of colorectal cancer; Colon Cancer
  
• Omega-3 Fatty Acid Status in Morbid Obesity Before and After Surgical Treatment
  ClinicalTrials.gov Identifier: NCT00558532 - Recruiting
  Morbid Obesity; Cardiovascular Disease; Fatty Acid Levels
  
• Suberoylanilide Hydroxamic Acid and Capecitabine in Treating Patients with Metastatic Or Unresectable Solid Tumors
  ClinicalTrials.gov Identifier: NCT00121277 - Active, not recruiting
  unspecified adult solid tumor, protocol specific
  
• Lactic Acid in the Rectum and Life-Threatening Infection.
  ClinicalTrials.gov Identifier: NCT00197938 - Recruiting
  Septic Shock
  
• Suberoylanilide Hydroxamic Acid in Treating Patients With Advanced Solid Tumors That Have Not Responded to Previous Therapy
  ClinicalTrials.gov Identifier: NCT00005634 - Active, not recruiting
  Leukemia; Lymphoma; Prostate Cancer; Multiple Myeloma; Eye Cancer
  
• Dimethylxanthenone Acetic Acid in Treating Patients With Solid Tumors
  ClinicalTrials.gov Identifier: NCT00003697 - Active, not recruiting
  unspecified adult solid tumor, protocol specific
  
• Pilot Study to Evaluate Nucleic Acid Amplification Methods in the Diagnosis and Management of Active TB
  ClinicalTrials.gov Identifier: NCT00023439 - Recruiting
  Tuberculosis
  
• Study of Treatment and Metabolism in Patients With Urea Cycle Disorders
  ClinicalTrials.gov Identifier: NCT00004307 - Recruiting
  Amino Acid Metabolism, Inborn Errors
  
• Study of Zoledronic Acid for Patients With Hormone-Sensitive Bone Metastases From Prostate Cancer
  ClinicalTrials.gov Identifier: NCT00242567 - Recruiting
  Prostate Cancer
  
• Suberoylanilide Hydroxamic Acid in Treating Patients With Recurrent or Persistent Ovarian Epithelial or Primary Peritoneal Cancer
  ClinicalTrials.gov Identifier: NCT00132067 - Active, not recruiting
  recurrent ovarian epithelial cancer; peritoneal cavity cancer
  
• Higher Frequency Zoledronic Acid in the Treatment of Multiple Myeloma
  ClinicalTrials.gov Identifier: NCT00263484 - Recruiting
  Multiple Myeloma
  
• Painful HIV Neuropathy and Alpha-Lipoic Acid
  ClinicalTrials.gov Identifier: NCT00079807 - Active, not recruiting
  HIV; Peripheral Neuropathy
  
• Ursodesoxycholic Acid in the Treatment of Duodenal Adenomas in FAP Patients.
  ClinicalTrials.gov Identifier: NCT00134758 - Recruiting
  Adenomatous Polyposis Coli; Adenoma
  
• Study of Zoledronic Acid Administered Monthly Versus Every 3 Months in Multiple Myeloma and Breast Cancer Patients Who Were Treated With Zoledronic Acid the Prior Year
  ClinicalTrials.gov Identifier: NCT00424983 - Recruiting
  Multiple Myeloma; Breast Cancer
  
• Clinical and Laboratory Study of Methylmalonic Acidemia
  ClinicalTrials.gov Identifier: NCT00078078 - Recruiting
  Amino Acid Metabolism; Inborn Errors
  
• Functional and Molecular Characterisation of Oesophageal Distal Epithelium: Correlations With Acid and Non Acid Reflux
  ClinicalTrials.gov Identifier: NCT00231881 - Recruiting
  Gastro-Oesophageal Reflux
  
• Safety Study of rhASM Enzyme Replacement Therapy in Adults With Acid Sphingomyelinase Deficiency (Niemann-Pick Disease)
  ClinicalTrials.gov Identifier: NCT00410566 - Recruiting
  Acid Sphingomyelinase Deficiency; Niemann-Pick Disease
  
• Paclitaxel, Folic Acid, and Lometrexol in Treating Patients With Locally Advanced or Metastatic Solid Tumors
  ClinicalTrials.gov Identifier: NCT00024310 - Active, not recruiting
  Drug Toxicity; unspecified adult solid tumor, protocol specific
  
• Suberoylanilide Hydroxamic Acid in Treating Patients With Progressive Stage IV Breast Cancer
  ClinicalTrials.gov Identifier: NCT00132002 - Active, not recruiting
  Male Breast Cancer; stage IV breast cancer; recurrent breast cancer
  
• The Effect of Fatty Acid Composition on Energy Intake and Satiety
  ClinicalTrials.gov Identifier: NCT00242021 - Active, not recruiting
  Obesity
  
• Tamoxifen Versus Anastrozole, Alone or in Combination With Zoledronic Acid
  ClinicalTrials.gov Identifier: NCT00295646 - Active, not recruiting
  Breast Cancer
  
• Phase II Randomized Study of Early Surgery vs Multiple Sequential Antiepileptic Drug Therapy for Infantile Spasms Refractory to Standard Treatment
  ClinicalTrials.gov Identifier: NCT00004758 - Completed
  Spasms, Infantile; Epilepsy
  
• Suberoylanilide Hydroxamic Acid in Treating Patients With Metastatic and/or Locally Advanced or Locally Recurrent Thyroid Cancer
  ClinicalTrials.gov Identifier: NCT00134043 - Active, not recruiting
  follicular thyroid cancer; insular thyroid cancer; medullary thyroid cancer; papillary thyroid cancer; Thyroid Cancer
  
• Aspirin and/or Folic Acid in Preventing Recurrent Colorectal Polyps
  ClinicalTrials.gov Identifier: NCT00033319 - Active, not recruiting
  prevention of colorectal cancer; Colon Cancer; Rectal Cancer
  
• 24 Month Extension to Efficacy and Safety of AEB071 Plus Tacrolimus (Converted to Mycophenolic Acid After 3 Months) in Renal Transplant Patients(Converted to Mycophenolic Acid After 3 Months) in Renal Transplant Patients
  ClinicalTrials.gov Identifier: NCT00555789 - Recruiting
  Kidney Transplantation
  
• Nicotinic Acid - Pharmacokinetics, Pharmacodynamics, Receptor Expression
  ClinicalTrials.gov Identifier: NCT00176020 - Not yet recruiting
  Nicotinic Acid; Flush Symptom; Pharmacodynamic; Pharmacokinetic
  
• D4T or Abacavir Plus Vitamin Enhancement (DAVE)
  ClinicalTrials.gov Identifier: NCT00143702 - Recruiting
  Elevated Lactic Acid
  
• Fatty Acid Binding Protein 2 (FABP2) Ancillary Proposal
  ClinicalTrials.gov Identifier: NCT00256633 - Active, not recruiting
  Type 2 Diabetes Mellitus
  
• Efficacy of Weekly Versus Daily Folic Acid Supplementation
  ClinicalTrials.gov Identifier: NCT00394862 - Active, not recruiting
  Neural Tube Defects
  
• Effect of Acid Reflux on Respiratory Physiology During Exercise in Athletes With GER-Response to Acid Suppression
  ClinicalTrials.gov Identifier: NCT00444236 - Not yet recruiting
  Exercise Triggered Asthma; Gastroesophageal Reflux
  
• Inhibition of Gastric Acid is the Key to Satisfactory Relief of Symptoms With Esomeprazole in NUD Patients
  ClinicalTrials.gov Identifier: NCT00222131 - Active, not recruiting
  Indigestion
  
• Study of Tauroursodeoxycholic Acid for Hepatobiliary Disease in Cystic Fibrosis
  ClinicalTrials.gov Identifier: NCT00004441 - Recruiting
  Cystic Fibrosis
  
• Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Efficacy and Pharmacokinetics of Myozyme in Patients with Late-Onset Pompe Disease.
  ClinicalTrials.gov Identifier: NCT00158600 - Active, not recruiting
  Pompe Disease (Late-onset); Glycogen storage disease type II (GSD-II); Acid Maltase Deficiency Disease; Glycogenosis 2
  
• Suberoylanilide Hydroxamic Acid in Treating Patients With Relapsed or Refractory Advanced Hodgkin''s Lymphoma
  ClinicalTrials.gov Identifier: NCT00132028 - Active, not recruiting
  recurrent adult Hodgkin''s lymphoma; stage IV adult Hodgkin''s lymphoma; adult lymphocyte depletion Hodgkin''s lymphoma; ...
  
• Efficacy and Safety of AEB071 Plus Tacrolimus (Converted to Mycophenolic Acid After 3 Months), in Renal Transplant Patients
  ClinicalTrials.gov Identifier: NCT00403416 - Active, not recruiting
  Kidney Transplantation
  
• Comparison of Acid Reflux at Two Levels in the Esophagus Using the BRAVO Capsule
  ClinicalTrials.gov Identifier: NCT00579410 - Active, not recruiting
  Esophagitis; Inflammation; Gastritis; Abdominal Pain; Heartburn
  
• Epsilon-Aminocaproaic Acid to Reduce the Need for Blood Transfusions During and Following Spine Surgery
  ClinicalTrials.gov Identifier: NCT00320619 - Active, not recruiting
  Scoliosis; Kyphosis; Lordosis; Spondylitis; Spinal Stenosis
  
• Evaluation of Efficacy and Safety of Omacor (Omega-3-Acid Ethyl Esters) as Add-on Therapy in Hypertriglyceridemic Subjects Treated With Antara (Fenofibrate)
  ClinicalTrials.gov Identifier: NCT00246636 - Active, not recruiting
  Hypertriglyceridemia
  
• Study on Amino Acid Uptake in Brain Tumors
  ClinicalTrials.gov Identifier: NCT00204295 - Active, not recruiting
  Brain Neoplasms
  
• Effects of Fatty Acid Supplementation on Substance Dependent Individuals
  ClinicalTrials.gov Identifier: NCT00312455 - Active, not recruiting
  Substance-Related Disorders
  
• A Study of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients With Solid Tumors
  ClinicalTrials.gov Identifier: NCT00373490 - Active, not recruiting
  Tumors