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A Study of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients with Malignant Lymphoma - Article


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Alpha-Lipoic Acid

dihydrolipoic acid; lipoic acid; lipolate; thiotic acid

Clinical Trial: A Study of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients with Malignant Lymphoma

This study is currently recruiting patients.
Verified by Merck August 2005

Sponsored by: Merck
Information provided by: Merck
ClinicalTrials.gov Identifier: NCT00127140

Purpose

The primary purpose of this trial is to determine the maximum tolerated dose (MTD), or the maximum acceptable dose (MAD) and evaluate the dose limiting toxicity (DLT) of oral suberoylanilide hydroxamic acid in patients with malignant lymphoma.
Condition Intervention Phase
Malignant Lymphoma
  Drug: MK0683, Suberoylanilide hydroxamic acid (SAHA)
 Phase I

MedlinePlus related topics:  Lymphoma

Study Type: Interventional
Study Design: Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Safety Study

Eligibility

Ages Eligible for Study:  20 Years   -   75 Years,  Genders Eligible for Study:  Both
Criteria

Inclusion Criteria:

  • Patients who relapsed after complete or partial response, or ineffective in previous chemotherapy

Exclusion Criteria:

  • Patients with history of chemotherapy, antibody therapy, radiotherapy, during the previous 4 weeks (6 months for radioisotope-labeled antibody)
  • Any uncontrolled concomitant illness
  • Are pregnant or breast-feeding
  • Serious drug or food allergy

Location and Contact Information

Please refer to this study by ClinicalTrials.gov identifier  NCT00127140

Call For Information      +81-3-5203-8218 

Japan, Chuoku
      Call For Site Information, Tokyo,  Chuoku,  103-8416,  Japan; Recruiting

Study chairs or principal investigators

Medical Monitor,  Study Director,  Merck   

More Information

Study ID Numbers:  2005_041
Last Updated:  August 19, 2005
Record first received:  August 3, 2005
ClinicalTrials.gov Identifier:  NCT00127140
Health Authority: Japan: Ministry of Health, Labor and Welfare
ClinicalTrials.gov processed this record on 2005-08-23


Source: ClinicalTrials.gov
Cache Date: August 24, 2005


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