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Medicinal Plant Use for Treating Inflammation Among Dominicans in New York City and the Dominican Republic - Article


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Vaginal Inflammation


Clinical Trial: Medicinal Plant Use for Treating Inflammation Among Dominicans in New York City and the Dominican Republic

This study is currently recruiting patients.

Sponsored by: National Center for Complementary and Alternative Medicine (NCCAM)
Information provided by: National Center for Complementary and Alternative Medicine (NCCAM)

Purpose

The purpose of this study is to investigate and compare the use of herbal medicine among Dominicans in New York City and the Dominican Republic.

Condition
Inflammation

MedlinePlus consumer health information 

Study Type: Observational
Study Design: Natural History, Cross-Sectional, Defined Population, Retrospective/Prospective Study

Official Title: Dominican Herbal Medicine: Plants Used for Inflammation

Further Study Details: 

Expected Total Enrollment:  420

Study start: March 2005;  Expected completion: January 2008
Last follow-up: May 2007;  Data entry closure: November 2007

According to the 2000 U.S. Census Report, Dominicans constitute the largest Hispanic immigrant group in New York City. Studies have shown that immigrants' use of traditional and herbal medicine is close to that of native-born Americans. However, minority immigrants often have limited access to traditional health care; as a result, they may be more likely to consult with traditional healers and use medicinal plants than nonimmigrants. This study is designed to increase knowledge about immigrants’ health and to contribute to more culturally-sensitive health care. The purpose of this study is to determine medical plant knowledge and use among Dominican traditional healers and patients in New York City and in the Dominican Republic.

This study will comprise two parts. In Part I, Dominican medicinal plant users and Dominican traditional healers in New York City will be questioned about the medicinal plant species they know and how they are used for prevalent illnesses. The same number of participants will be interviewed in the Dominican Republic, allowing for detailed comparisons between the two study sites.

In Part II, the most frequently-cited medicinal plant species will be subjected to a thorough literature review on their pharmacologic activity and the chemical composition of their active constituents. Two in vitro assays will be used to measure the anti-inflammatory activity of certain plant extracts, and their anti-inflammatory compounds will be isolated and characterized for the purpose of standardization of active extracts. On the basis of these results, recommendations will be formulated for future studies and community use of selected medicinal plant species.

Eligibility

Ages Eligible for Study:  18 Years and above,  Genders Eligible for Study:  Both

Accepts Healthy Volunteers

Criteria

Inclusion Criteria:

  • Dominican ethnicity
  • Have knowledge of Dominican medicinal plants

Location and Contact Information

Please refer to this study by ClinicalTrials.gov identifier  NCT00109980

Ina Vandebroek, PhD      718-817-8941    etnobotanica@nybg.org
Michael J. Balick, PhD      718-817-8763    mbalick@nybg.org

New York
      Associates in Internal Medicine Clinic, New York-Presbyterian Hospital, Columbia University, New York City,  New York,  10032,  United States; Recruiting
Rafael Lantigua, MD  212-305-6262    ral4@columbia.edu 

Study chairs or principal investigators

Michael J. Balick, PhD,  Principal Investigator,  Institute of Economic Botany, the New York Botanical Garden   

More Information

Publications

Balick MJ, Lee R. Looking within: urban ethnomedicine and ethnobotany. Altern Ther Health Med. 2001 Jul-Aug;7(4):114-5. No abstract available.

Fugh-Berman A, Balick MJ, Kronenberg F, Ososki AL, O'Connor B, Reiff M, Roble M, Lohr P, Brosi BJ, Lee R. Treatment of fibroids: the use of beets (Beta vulgaris) and molasses (Saccharum officinarum) as an herbal therapy by Dominican healers in New York City. J Ethnopharmacol. 2004 Jun;92(2-3):337-9. No abstract available.

Ososki AL, Lohr P, Reiff M, Balick MJ, Kronenberg F, Fugh-Berman A, O'Connor B. Ethnobotanical literature survey of medicinal plants in the Dominican Republic used for women's health conditions. J Ethnopharmacol. 2002 Mar;79(3):285-98.

Study ID Numbers:  1-R21-AT001889-01A1
Record last reviewed:  May 2005
Last Updated:  May 3, 2005
Record first received:  May 3, 2005
ClinicalTrials.gov Identifier:  NCT00109980
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-05-17


Source: ClinicalTrials.gov
Cache Date: May 18, 2005


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September 7, 2008



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