Gamma-Linolenic Acid (GLA)

Clinical Trial: Lactic Acid in the Rectum and Life-Threatening Infection.

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Purpose
Eligibility
Location and Contact Information
More Information

This study is not yet open for patient recruitment.
Verified by Copenhagen University Hospital at Herlev September 2005

Sponsored by:	Copenhagen University Hospital at Herlev
Information provided by:	Copenhagen University Hospital at Herlev
ClinicalTrials.gov Identifier:	NCT00197938

Purpose

Life-threatening infection impairs bloodflow to the gut, thereby causing less delivery of oxygen. This leads to increased formation of lactic acid.

We hypothesize, that the more serious the condition, the higher the concentration of lactic acid will be, thus relating to the risk of multiple organ failure or death.

Condition	Intervention
Septic Shock	Procedure: Measurement of rectal lactic acid.

MedlinePlus related topics: Sepsis

Study Type: Observational
Study Design: Natural History, Cross-Sectional, Defined Population, Prospective Study

Official Title: Does the Concentration of L-Lactate in the Rectum Correlate with Mortality and Morbidity in Patients with Septic Shock?

Further Study Details:

Expected Total Enrollment: 150

Study start: November 2005; Expected completion: December 2006
Last follow-up: December 2006; Data entry closure: December 2006

Eligibility

Ages Eligible for Study: 18 Years and above, Genders Eligible for Study: Both

Criteria

Inclusion Criteria:

Fluid resuscitated septic shock < 24 h.

Exclusion Criteria:

Septic shock > 24 h.
Pathology in the rectum.
Bleeding per rectum.
Limitation of therapy
Where informed consent from relatives cannot be obtained.

Location and Contact Information

Please refer to this study by ClinicalTrials.gov identifier NCT00197938

Michael Ibsen, MD +45 44 88 35 95 micibs@dadlnet.dk
Anders Perner, MD, PhD +45 44 88 38 39 ap@dadlnet.dk

Denmark
Dept. of Intensive Care, Herlev University Hospital, Herlev, DK-2730, Denmark

Michael Ibsen, MD +45 44 88 35 95 micibs@dadlnet.dk

Dept. of Intensive Care, Glostrup University Hospital, Glostrup, DK-2600, Denmark

Thomas Mohr, MD, PhD +45 43 23 23 00

Dept. of Intensive Care, Gentofte University Hospital, Hellerup, DK-2900, Denmark

Lone Møller Poulsen, MD +45 39 77 37 73

Dept. of Intensive Care 4131, Rigshospitalet, Copenhagen, DK-2100, Denmark

Jørgen Wiis, MD +45 35 45 35 45

Finland
Dept. of Intensive Care, Tampere University Hospital, Tampere, 33521, Finland

Jyrki Tenhunen, MD, PhD +358 3 311 611

Study chairs or principal investigators

Anders Perner, MD, PhD, Study Chair, Dept. of Anaesthesia and Intensive Care, Herlev University Hospital, DK-2730 Herlev

More Information

Study ID Numbers: KA 05091m
Last Updated: September 19, 2005
Record first received: September 14, 2005
ClinicalTrials.gov Identifier: NCT00197938
Health Authority: Denmark: The Regional Committee on Biomedical Research Ethics
ClinicalTrials.gov processed this record on 2005-09-20

Source: ClinicalTrials.gov
Cache Date: September 21, 2005

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Lactic Acid in the Rectum and Life-Threatening Infection. - Article

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Gamma-Linolenic Acid (GLA)

Clinical Trial: Lactic Acid in the Rectum and Life-Threatening Infection.

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Purpose

Eligibility

Location and Contact Information

More Information

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Lactic Acid in the Rectum and Life-Threatening Infection. - Article

General Topics A-Z

Gamma-Linolenic Acid (GLA)

Clinical Trial: Lactic Acid in the Rectum and Life-Threatening Infection.

Jump to Section

Purpose

Eligibility

Location and Contact Information

More Information

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